Lupus eritematoso sistemico all'esordio complicato da un severo coinvolgimento multiorgano
| Autor: | Giorgia Russo, Silvia Forcellini, Mariangela Annaloro, Yuri Battaglia, Alessia Bortot |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
lcsh:Internal medicine
medicine.medical_specialty Renal function lcsh:RC870-923 Gastroenterology Malaise chemistry.chemical_compound Oliguria Internal medicine medicine Pharmacology (medical) lcsh:RC31-1245 Creatinine Proteinuria business.industry lcsh:Diseases of the genitourinary system. Urology medicine.disease Lupus Eritematoso Sistemico Rabdomiolisi chemistry Acute pancreatitis Hemoglobinuria medicine.symptom Insufficienza Renale Acuta business Rhabdomyolysis |
| Zdroj: | Giornale di Clinica Nefrologia e Dialisi, Vol 25, Iss 2 (2013) |
| ISSN: | 2705-0076 |
| DOI: | 10.33393/gcnd.2013.1019 |
| Popis: | The authors report the case of a 51-year-old man with a 1-month history of mild gastroenteritic symptoms, daily fever and malaise. The patient was febrile (38.5°C) and laboratory data showed renal failure (creatinine 2.5 mg/dL), proteinuria and hemoglobinuria. A 10-day antibiotic therapy was started since an infective gastrointestinal process was initially suspected. When autoimmune immunologic patterns, associated with renal, neurologic and hematologic signs, confirmed the diagnosis of systemic lupus erythematous the patient was infused with high-dose intravenous corticosteroids. Despite the treatment, the patient developed rhabdomyolysis, acute pancreatitis, worsening of renal function (creatinine 5.5 mg/dL) to oliguria, and marked cognitive impairment. Our case focuses on the importance of an early recognition of laboratory and anamnestic data that may suggest a systemic autoimmune involvement, so as to rapidly undertake an aggressive immunosuppressive therapy. |
| Databáze: | OpenAIRE |
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