Nanotechnological approach to delivering nutraceuticals as promising drug candidates for the treatment of atherosclerosis

Autor: D. Sakthi Kumar, Ankita Borah, Sindhu C Pillai, Eden Mariam Jacob
Rok vydání: 2021
Předmět:
Drug
medicine.medical_specialty
Polymers
media_common.quotation_subject
Chemistry
Pharmaceutical
anti-inflammatory drugs
Anti-Inflammatory Agents
Pharmaceutical Science
Metal Nanoparticles
02 engineering and technology
RM1-950
Review Article
030226 pharmacology & pharmacy
03 medical and health sciences
0302 clinical medicine
Nutraceutical
Drug Delivery Systems
medicine
Humans
Clinical efficacy
Intensive care medicine
media_common
nutraceuticals
bio-markers
business.industry
Atherosclerotic disease
General Medicine
021001 nanoscience & nanotechnology
Atherosclerosis
NPs
Lipids
Plaque
Atherosclerotic
Heart Disease Risk Factors
Drug delivery
Dietary Supplements
Nanoparticles
Therapeutics. Pharmacology
Endothelium
Vascular
Inflammation Mediators
0210 nano-technology
business
Present generation
Foam Cells
Research Article
Zdroj: Drug Delivery
article-version (VoR) Version of Record
Drug Delivery, Vol 28, Iss 1, Pp 550-568 (2021)
ISSN: 1521-0464
Popis: Atherosclerosis is Caesar’s sword, which poses a huge risk to the present generation. Understanding the atherosclerotic disease cycle would allow ensuring improved diagnosis, better care, and treatment. Unfortunately, a highly effective and safe way of treating atherosclerosis in the medical community remains a continuous challenge. Conventional treatments have shown considerable success, but have some adverse effects on the human body. Natural derived medications or nutraceuticals have gained immense popularity in the treatment of atherosclerosis due to their decreased side effects and toxicity-related issues. In hindsight, the contribution of nutraceuticals in imparting enhanced clinical efficacy against atherosclerosis warrants more experimental evidence. On the other hand, nanotechnology and drug delivery systems (DDS) have revolutionized the way therapeutics are performed and researchers have been constantly exploring the positive effects that DDS brings to the field of therapeutic techniques. It could be as exciting as ever to apply nano-mediated delivery of nutraceuticals as an additional strategy to target the atherosclerotic sites boasting high therapeutic efficiency of the nutraceuticals and fewer side effects.
Databáze: OpenAIRE
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