Risk assessment of patient factors and medications for drug-related problems from a prospective longitudinal study of newborns admitted to a neonatal intensive care unit in Brazil
| Autor: | Rand Randall Martins, Marco Edoardo Tavares dos Santos, Ramon Duarte Leopoldino, Tatiana Xavier da Costa, Antonio Gouveia Oliveira |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Longitudinal study Neonatal intensive care unit Drug-Related Side Effects and Adverse Reactions 030226 pharmacology & pharmacy Risk Assessment health & safety 03 medical and health sciences 0302 clinical medicine Pharmacotherapy Risk Factors Intensive care Intensive Care Units Neonatal medicine neonatal intensive & critical care Humans Medication Errors 030212 general & internal medicine Longitudinal Studies Prospective Studies Adverse effect Hospitals Teaching business.industry Research Infant Newborn Gestational age Paediatrics General Medicine Length of Stay adverse events Drug Utilization Clinical pharmacy Logistic Models Emergency medicine Multivariate Analysis Female Risk assessment business Pharmacy Service Hospital Brazil |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | ObjectiveTo identify patient factors and medications associated with the occurrence of drug-related problems (DRPs) in neonates admitted to neonatal intensive care units (NICUs).DesignProspective, longitudinal study.SettingNICU of a teaching hospital in Brazil.ParticipantsData were collected from the records of the clinical pharmacy service of all neonates admitted between April 2014 and January 2017, excluding neonates with length of stay in the NICU Primary outcome measuresOccurrence of one or more DRP (conditions interfering in the patient’s pharmacotherapy with potential undesired clinical outcomes).ResultsThe study observed 600 neonates who had a median length of stay in the NICU of 13 days (range 2–278 days). DRPs were identified in most neonates (60.5%). In a multivariate logistic regression model, the factors independently associated with DRP were gestational age (adjusted OR (AOR) 0.85, 95% CI 0.81 to 0.89), 5 min Apgar ConclusionsGestational age, 5 min Apgar |
| Databáze: | OpenAIRE |
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