Fournier’s gangrene: a clinical presentation of necrotizing fasciitis after bone marrow transplantation
| Autor: | Emilio Paolo Alessandrino, G P Vignoli, D Caldera, Carlo Bernasconi, Paolo Bernasconi, Luca Malcovati, M R Gaviglio, Giovanni Martinelli, G Borroni, A Colombo |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Perineum Vulva Sepsis Abdominal wall medicine Humans Pseudomonas Infections Fasciitis Abdominal Muscles Bone Marrow Transplantation Ultrasonography Gangrene Transplantation business.industry Hematology Staphylococcal Infections medicine.disease Surgery Leukemia Myeloid Acute Leukemia medicine.anatomical_structure Pseudomonas aeruginosa Scrotum Female business Complication Fournier Gangrene |
| Zdroj: | Bone Marrow Transplantation. 22:1023-1026 |
| ISSN: | 1476-5365 0268-3369 |
| DOI: | 10.1038/sj.bmt.1701438 |
| Popis: | Three patients with ANLL developed Fournier's gangrene as an early complication after allo-BMT (two cases) and auto-BMT (one case); two patients were in first CR, the third had resistant disease. Patients developed fever, perineal pain, swelling and blistering of the genital area. Pseudomonas aeruginosa was isolated from the lesions and patients received systemic antibiotic therapy, surgical debridement and medication with potassium permanganate solution. Two patients made a complete recovery although one died of sepsis. The third had progressive involvement of the abdominal wall and later died of leukemia. Early diagnosis of this disorder and prompt initiation of appropriate therapy can prevent progression of this acute necrotizing infection. |
| Databáze: | OpenAIRE |
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