Growth, Growth Velocity and Adult Height in Mexican Girls with Turner's Syndrome
| Autor: | Raúl Calzada León, Joel Oyoqui, María de la Luz Ruiz Reyes, Nelly Altamirano Bustamante, Victoria Del Castillo Ruiz, Carlos Robles Valdés |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Pediatrics
medicine.medical_specialty Percentile medicine.drug_class Endocrinology Diabetes and Metabolism medicine.medical_treatment Turner Syndrome Growth Drug Administration Schedule Cohort Studies Growth velocity Endocrinology Age Determination by Skeleton medicine Humans Mexico Progesterone Sex Chromosome Aberrations Gynecology Chromosomes Human X Estrogens Conjugated (USP) Fetal Growth Retardation Growth retardation Progestogen business.industry Puberty Estrogens Bone age Turner's syndrome Body Height Adult height Socioeconomic Factors Estrogen Karyotyping Pediatrics Perinatology and Child Health Female business |
| Zdroj: | Journal of Pediatric Endocrinology and Metabolism. 16 |
| ISSN: | 2191-0251 0334-018X |
| DOI: | 10.1515/jpem.2003.16.8.1165 |
| Popis: | This was a prospective, longitudinal and descriptive study of 117 Mexican girls with Turner's syndrome (TS) followed from diagnosis to 18 years old. Height, weight and growth velocity were evaluated every 4-6 months, and bone age was assessed annually. Adult height was reached in 87 girls. All the girls were treated during 1 year with conjugated estrogens at bone age of 12 years, and subsequently with mixed estrogen/progestogen. Growth retardation in girls with TS is apparent at birth (2.7 ′ 0.9 kg and 46.3 ′ 5.0 cm) and in childhood, but becomes most marked when puberty would normally occur. Mean growth velocity was less than 25 t h percentile from birth to 2 years, less than 10 t h percentile between 3-9 years, and less than 3 r d percentile from 10 to 18 years of age. Final adult height was 136.9 ′ 5.5 cm, but it is affected by the particular karyotype: 46,Xi(Xq): 134.5 cm, 45,XO: 137.3 cm, and 45XO/46,XX: 139 cm. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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