Radiologic manifestation of histiocytic lymphoma in the skeletal and central nervous system
| Autor: | Hamlin Dj, Burgener Fa |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Nerve root Adolescent Central nervous system Bone Neoplasms Lesion medicine Humans Radiology Nuclear Medicine and imaging Femur Spinal Cord Neoplasms Child Pelvis Aged Retrospective Studies medicine.diagnostic_test business.industry Brain Neoplasms Middle Aged Spinal cord Radiography medicine.anatomical_structure Pagetoid Female Lymphoma Large B-Cell Diffuse medicine.symptom business Myelography |
| Zdroj: | RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 134(1) |
| ISSN: | 1438-9029 |
| Popis: | The radiographic manifestation of histiocytic lymphoma in the skeletal and central nervous system of 112 non-selected patients were reviewed in a retrospective study. Histiocytic lymphoma metastatic to bone and brain are late manifestations of the disease occurring in 15 and 4%, respectively. Involvement of the spinal cord and nerve roots is found in 6% and represents often the initial manifestation of the disease. Histiocytic lymphoma of brain presents angiographically as avascular mass without site predilection and on contrast enhanced computer tomography as hyperdense lesion without necrotic center. On myelography an extradural mass or complete block is found. The most common skeletal locations are spine, pelvis, rib and femur. The ratio of multifocal to unifocal skeletal manifestations is approximately 2 to 1. The radiographic appearance varies from completely lytic, often associated with a soft tissue mass, to osteoblastic, often with Pagetoid features. Early recognition of histiocytic lymphoma manifestations is important to guarantee prompt institution of appropriate therapy since the disease can progress extremely rapidly. |
| Databáze: | OpenAIRE |
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