Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
| Autor: | Toshihiro Watanabe, Yoshimasa Sagane, Koichi Niwa, Takamasa Uchino, Tomonori Suzuki, Keita Hosoya, Shin-Ichiro Miyashita, Shura Karatsu, Yoichi Niimura, Ihsun Huang |
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| Rok vydání: | 2019 |
| Předmět: |
macromolecular substances
BoNT botulinum neurotoxin lcsh:Computer applications to medicine. Medical informatics medicine.disease_cause TC toxin complex Atomic force microscopy Protein structure Biochemistry Genetics and Molecular Biology Clostridium botulinum Microscopic image medicine Molecule lcsh:Science (General) Multidisciplinary Strain (chemistry) Chemistry Botulinum toxin complex Hemagglutinin Botulinum neurotoxin AFM atomic force microscopy Crystallography lcsh:R858-859.7 lcsh:Q1-390 |
| Zdroj: | Data in Brief Data in Brief, Vol 25, Iss, Pp-(2019) |
| ISSN: | 2352-3409 |
| DOI: | 10.1016/j.dib.2019.104193 |
| Popis: | This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin proteins (M-TC) and complex of M-TC and hemagglutinin subcomplex (L-TC). In this data article, the M and L-TC produced by serotype D strain 4947 were imaged by AFM. The M-TC molecule had a globular structure with a 30.5-nm diameter and a 2.1-nm height, while the L-TC molecule had a distinct structure in which several spheres were connected to a globular structure that was 40.7 nm in diameter and 3.5 nm in height. Keywords: Clostridium botulinum, Botulinum toxin complex, Atomic force microscopy, Protein structure |
| Databáze: | OpenAIRE |
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