Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ Screening

Autor:	Romain Duval, David Genest, Stéphanie Kolb, Christiane Garbay, Emmanuelle Braud
Rok vydání:	2009
Předmět:	Molecular Structure Chemistry Stereochemistry Drug Evaluation Preclinical Stereoisomerism General Chemistry Triazoles Molecular biology Structure-Activity Relationship Thiazoles Pyrimidines Click chemistry Combinatorial Chemistry Techniques cdc25 Phosphatases Enzyme Inhibitors
Zdroj:	Journal of Combinatorial Chemistry. 11:947-950
ISSN:	1520-4774 1520-4766
DOI:	10.1021/cc900140f
Popis:	UniVersite Paul Sabatier Toulouse III, Faculte des Sciences Pharmaceutiques, Laboratoire de Pharmacochimie des Substances Naturelles et Pharmacophores Redox, UMR152 IRD-UT3, 31062 Toulouse cedex 09, France, UniVersite Paris Descartes, UFR Biomedicale, Laboratoire de Pharmacochimie Moleculaire et Cellulaire, 45 rue des Saints-Peres, 75270 Paris, cedex 06, France, and INSERM U648, 45 rue des Saints-Peres, 75270 Paris, cedex 06, France
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e631451615ef05bea066aaf0ebf6185f https://doi.org/10.1021/cc900140f Zobrazit plný text záznamu