The secondarily generalized tonic-clonic seizure: a videotape analysis
| Autor: | William H. Theodore, Roger J. Porter, Susumu Sato, Edward Bromfield, Paul S. Albert, Orrin Devinsky, Kathy Kelley |
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| Rok vydání: | 1994 |
| Předmět: |
Generalized tonic-clonic seizure
Adult Male medicine.medical_specialty Time Factors Adolescent Typical absence Electroencephalography Tonic (physiology) Central nervous system disease Epilepsy medicine Humans Child medicine.diagnostic_test Brain Videotape Recording Middle Aged medicine.disease nervous system diseases Surgery Phase duration Anesthesia Marked heterogeneity Female Neurology (clinical) Epilepsy Tonic-Clonic Psychology |
| Zdroj: | Neurology. 44(8) |
| ISSN: | 0028-3878 |
| Popis: | We studied 120 generalized tonic-clonic seizures (GTCSs) in 47 patients with video-EEG telemetry. GTCSs were preceded by antecedent seizures, including 13 simple partial, 70 complex partial, 17 simple partial leading to complex partial, seven tonic, seven clonic, and one typical absence. We divided GTCSs into the following phases: onset of generalization, pretonic clonic, tonic, tremulousness, and clonic. The mean GTCS duration was 62 seconds. There was a nonsignificant trend toward longer duration on reduced antiepileptic drug doses. Marked heterogeneity in GTCS phenomenology was present; only 27% of seizures included all five phases. Individual phase duration and clinical expression, including tonic and clonic phases, was highly variable. The clinical phenomena suggest that multiple cortical and subcortical routes of spread may exist. When GTCSs last longer than 2 minutes, intravenous antiepileptic drug treatment should be initiated. |
| Databáze: | OpenAIRE |
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