Effects of intubation on coronary blood flow and myocardial oxygenation
| Autor: | Marjorie Raymond, John A. Bussell, Jack M. Matloff, Dhun H. Sethna, Emerson A. Moffitt, Richard J. Gray |
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| Rok vydání: | 1985 |
| Předmět: |
Male
medicine.medical_specialty Cardiac output medicine.medical_treatment Hemodynamics Blood Pressure Coronary Disease Anesthesia General Coronary artery disease Coronary circulation Oxygen Consumption Heart Rate Coronary Circulation Internal medicine Intubation Intratracheal medicine Humans Intubation Cardiac Output Coronary Artery Bypass Aged Ejection fraction Morphine business.industry Myocardium Stroke Volume General Medicine Middle Aged medicine.disease Anesthesiology and Pain Medicine medicine.anatomical_structure Blood pressure Anesthesia Lactates Vascular resistance Cardiology Female Halothane business |
| Zdroj: | Canadian Anaesthetists’ Society Journal. 32:105-111 |
| ISSN: | 1496-8975 0008-2856 |
| DOI: | 10.1007/bf03010032 |
| Popis: | Effects on haemodynamics and myocardial oxygenation of endotracheal intubation were examined in 17 patients after halothane induction and 12 after 1 mg X kg-1 of IV morphine. Six patients having each anaesthetic were pretreated with IV propranolol (0.1 mg X kg-1) 45 minutes earlier. Arterial and intracardiac pressures, cardiac output and total coronary sinus blood flow (CSBF), both by thermodilution, were determined plus arterial-coronary differences of oxygen, haemoglobin and lactate. Blood pressure (BP), heart rate and CSBF were recorded continuously during intubation. The subjects were candidates for coronary bypass grafts, but had good ventricular function (mean ejection fraction 0.68 +/- 0.13 SD). From their reduced levels after induction, BP, cardiac index and systemic vascular resistance increased to awake levels following intubation. Mean CSBF in nonbetablocked patients increased to awake level along with BP. More myocardial oxygen was extracted and consumed after intubation, but lactate extraction continued: these data are evidence of adequate oxygen supply. Induction with either halothane or morphine effectively prevented the hypertensive response to intubation. Acute beta blockade led to less increase in heart rate from intubation. |
| Databáze: | OpenAIRE |
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