Does CPAP treatment lead to gastroesophageal reflux in patients with moderate and severe OSA?

Autor: Hatice Kutbay Özçelik, Omer Uysal, Elif Arabaci, Levent Kart, Yusuf Kayar, Ahmet Danalioglu, Fatih Yakar
Přispěvatelé: ARABACI, ELİF
Rok vydání: 2016
Předmět:
Adult
Male
medicine.medical_specialty
Waist
Turkey
Polysomnography
medicine.medical_treatment
Severity of Illness Index
03 medical and health sciences
0302 clinical medicine
Severity of illness
medicine
Humans
Continuous positive airway pressure
Sleep Apnea
Obstructive
Continuous Positive Airway Pressure
medicine.diagnostic_test
business.industry
fungi
Reflux
General Medicine
Middle Aged
medicine.disease
OZCELIK H.
KAYAR Y.
DANALIOGLU A.
ARABACI E.
Uysal O.
YAKAR F.
KART L.
-Does CPAP treatment lead to gastroesophageal reflux in patients with moderate and severe OSA?-
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
cilt.274
ss.1223-1229
2017
nervous system diseases
respiratory tract diseases
Surgery
Obstructive sleep apnea
Treatment Outcome
Otorhinolaryngology
Anesthesia
Gastroesophageal Reflux
Female
030211 gastroenterology & hepatology
business
Body mass index
030217 neurology & neurosurgery
Zdroj: European Archives of Oto-Rhino-Laryngology. 274:1223-1229
ISSN: 1434-4726
0937-4477
Popis: Obstructive sleep apnea (OSA) leads to upper respiratory tract obstruction, causing increased abdominal-gastric pressure and decreased lower esophageal sphincter (LES) pressure and thus gastroesophageal reflux (GER). Continuous positive airway pressure (CPAP) is known to be an effective method for OSA treatment, but its effect on GER is still controversial. There are a very few studies investigating CPAP and GER relationship and performed based on pre- and post-treatment objective parameters of GER in patients with OSA. The study investigated the effect of CPAP treatment in patients with moderate and severe OSA without GER complaints on pre- and post-treatment objective GER parameters. The study included 25 patients with respiratory disturbance indices15 without reflux symptoms who had undergone polysomnography at sleep laboratory. Age, sex, body mass index (BMI), waist, and neck circumference of the patients were documented. DeMeester score, LES pressure, and polysomnography parameters were evaluated pre- and post-CPAP. The results were statistically evaluated, and p value0.05 is considered significant. Out of 25 patients, 21 were male (84 %) and mean age was 49.2 ± 8.6 (range 31-66). At the pre-CPAP phase, mean sphincter pressure was 22.2 ± 1.2 (range 8-73), and mean DeMeester score was 18 ± 15.5 (range 0.2-57). At the post-CPAP, mean sphincter pressure was 22.9 ± 1.6 (range 9-95), and mean DeMeester score was 16.3 ± 14.8 (range 0.2-55). No significant difference (p 0.05) was found comparing pre-CPAP and post-CPAP measurements. Objective criteria show that CPAP treatment does not cause reflux in patients with OSA. Unlike studies reported in the literature, this conclusion has been reached by pre- and post-CPAP assessments.
Databáze: OpenAIRE
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