Improvement in exercise capacity and exercise hemodynamics 3 months after double-balloon, catheter balloon valvuloplasty treatment of patients with symptomatic mitral stenosis
| Autor: | A Gonzalez, S H Rahimtoola, Charles R. McKay, K Parise, T Odom-Maryon, C L Reid, Adam Kotlewski, D T Kawanishi |
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| Rok vydání: | 1988 |
| Předmět: |
Adult
Male Cardiac Catheterization medicine.medical_specialty Cardiac output Physical Exertion Hemodynamics Catheterization Physiology (medical) Internal medicine Mitral valve medicine Humans Mitral Valve Stenosis Treadmill Pulmonary wedge pressure Aged business.industry Cineradiography Angiocardiography Mitral Valve Insufficiency Middle Aged Balloon valvuloplasty medicine.disease Catheter Stenosis medicine.anatomical_structure Anesthesia Exercise Test Cardiology Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Circulation. 77:1013-1021 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/01.cir.77.5.1013 |
| Popis: | Clinical status, exercise treadmill performance, and hemodynamics were determined in 24 patients with symptomatic mitral stenosis before catheter balloon valvuloplasty (CBV) and at 3 months follow-up. Hemodynamic determinations at rest showed that mitral CBV performed by the double-balloon technique resulted in significant immediate decreases in mean pulmonary arterial wedge pressure (28 +/- 7 to 16 +/- 5 mm Hg, p less than .01), mean pulmonary arterial pressure (41 +/- 11 to 33 +/- 10 mm Hg, p less than .05), and mitral valve gradient (16 +/- 7 to 6 +/- 3 mm Hg, p less than .01), and significant increases in cardiac output (4.3 +/- 1.1 to 5.0 +/- 1.4 liters/min, p less than .01). Mitral valve area increased from 1.0 +/- 0.3 to 2.2 +/- 0.7 cm2 (p less than .01). The mitral valve area was unchanged (2.0 +/- 0.7 cm2, p = NS) at 3 months. The lower pulmonary arterial wedge pressure, pulmonary arterial pressure, and mitral valve gradient persisted at 3 month follow-up catheterization. Clinical examinations showed that before CBV, 21 of 24 patients were in New York Heart Association functional class III or IV; 3 months after CBV, 22 patients were in class I or II. Before CBV, the mean exercise treadmill time was 5.9 +/- 3.2 min and it had increased to 9.8 +/- 2.9 min (p less than .01) by the 3 month follow-up.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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