Changes in brain glutathione levels during postnatal development in the rat
| Autor: | Joanna Tolputt, Keith J. Collard, Devika Nanda |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Cerebellum Antioxidant Period (gene) medicine.medical_treatment Synaptogenesis Biology Neuroprotection Brain Ischemia chemistry.chemical_compound Developmental Neuroscience Internal medicine Cortex (anatomy) medicine Animals Rats Wistar Cerebral Cortex Brain Glutathione Rats medicine.anatomical_structure Endocrinology Liver chemistry Cerebral cortex Disease Susceptibility Neuroscience Developmental Biology |
| Zdroj: | Developmental Brain Research. 94:238-241 |
| ISSN: | 0165-3806 |
| DOI: | 10.1016/s0165-3806(96)80016-2 |
| Popis: | The concentration of glutathione in the rat cerebral cortex, cerebellum and liver was examined during postnatal development. The glutathione level in both brain regions was low at the earliest age studied (postnatal day (PND) 3) and peaked at PND7. In the liver, the glutathione level was maximal at PND30. The glutathione peak at PND7 occurs during a period of intense synaptogenesis and may be related to a neuroprotective role during brain development. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect