Chronic pulmonary hypertension shortens the duration of mitral annular systolic and diastolic tissue doppler signals
Autor: | Beth Gulyasy, Maria Dolores Candales, Angel López-Candales, Kathy Edelman |
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Rok vydání: | 2011 |
Předmět: |
Adult
Male medicine.medical_specialty Time Factors Systole Hypertension Pulmonary Diastole Ventricular Function Left Ventricular Dysfunction Left Young Adult Heart Rate Predictive Value of Tests Internal medicine Mitral valve Heart rate medicine Humans Radiology Nuclear Medicine and imaging Ventricular remodeling Aged Retrospective Studies Aged 80 and over Echocardiography Doppler Pulsed Observer Variation Ejection fraction Ventricular Remodeling business.industry Reproducibility of Results Stroke Volume Stroke volume Middle Aged Pennsylvania medicine.disease Pulmonary hypertension medicine.anatomical_structure Chronic Disease Linear Models Cardiology Mitral Valve Female Cardiology and Cardiovascular Medicine business |
Zdroj: | The International Journal of Cardiovascular Imaging. 28:513-519 |
ISSN: | 1573-0743 1569-5794 |
DOI: | 10.1007/s10554-011-9826-1 |
Popis: | Some data suggests that both left ventricular (LV) systolic and diastolic function are impaired in patients with chronic pulmonary hypertension (cPH); however, a clear understanding of these specific abnormalities remains poorly characterized. LV systolic and diastolic function as well as LV myocardial performance index (MPI) were obtained and compared to total duration of mitral annular (MA) TDI systolic (MASTDId) and diastolic (MADTDId) measurements, corrected for heart rate, in 20 controls (Group I: mean 53 ± 18 years) and 30 patients (Group II: mean 55 ± 14 years) with cPH. Group II patients had relatively faster heart rates (75 ± 14 bpm vs. 63 ± 12 bpm; P < 0.003), higher LV ejection fraction (78 ± 10% vs. 68 ± 6%; P < 0.0004), similar MA systolic excursion (1.4 ± 0.2), unchanged MA TDI Ea/Aa ratios (0.86 ± 0.46 vs. 1.05 ± 0.41; P = 0.15), significantly higher LV MPI (0.98 ± 0.56 vs. 0.60 ± 0.11; P < 0.004), with a significantly shorter heart rate corrected MASTDId (251 ± 66 ms vs. 305 ± 30 ms; P < 0.001) and MADTDId (378 ± 87 ms vs. 497 ± 114 ms; P < 0.0001) than Group I. It appears that cPH shortens the total duration of both MA systolic and diastolic TDI intervals. Whether this is a result of altered LV geometry and/or confounded by the presence of relatively faster heart rates in cPH patients will require further study. |
Databáze: | OpenAIRE |
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