Metamorphopsia Associated with Branch Retinal Vein Occlusion
| Autor: | Akihito Uji, Tomoyoshi Fujita, Kazuyuki Hirooka, Koichiro Manabe, Chieko Shiragami, Yuki Nakano, Rie Osaka, Yuki Muraoka, Akitaka Tsujikawa |
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| Rok vydání: | 2016 |
| Předmět: |
Male
0301 basic medicine Visual acuity genetic structures Vision Visual Acuity Social Sciences lcsh:Medicine Infographics Diagnostic Radiology chemistry.chemical_compound 0302 clinical medicine Medicine and Health Sciences Psychology Prospective Studies lcsh:Science Tomography Insect Metamorphosis Multidisciplinary Radiology and Imaging Retinal detachment Charts medicine.anatomical_structure Evaluation Studies as Topic Retinal Disorders Sensory Perception Female Anatomy medicine.symptom Tomography Optical Coherence Research Article medicine.drug Computer and Information Sciences medicine.medical_specialty Imaging Techniques Ocular Anatomy Vision Disorders Research and Analysis Methods Retina Serous Retinal Detachment 03 medical and health sciences Ocular System Diagnostic Medicine Ranibizumab Ophthalmology Retinal Vein Occlusion medicine Humans Metamorphopsia Aged Metamorphosis business.industry Data Visualization lcsh:R Retinal Detachment Biology and Life Sciences Retinal Vessels Retinal medicine.disease Holometabolism eye diseases Surgery 030104 developmental biology chemistry Cardiovascular Anatomy 030221 ophthalmology & optometry Eyes Blood Vessels Branch retinal vein occlusion lcsh:Q sense organs business Head Zoology Entomology Neuroscience Developmental Biology |
| Zdroj: | PLoS ONE, Vol 11, Iss 4, p e0153817 (2016) PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0153817 |
| Popis: | Purpose To apply M-CHARTS for quantitative measurements of metamorphopsia in eyes with acute branch retinal vein occlusion (BRVO) and to elucidate the pathomorphology that causes metamorphopsia. Methods This prospective study consisted of 42 consecutive patients (42 eyes) with acute BRVO. Both at baseline and one month after treatment with ranibizumab, metamorphopsia was measured with M-CHARTS, and the retinal morphological changes were examined with optical coherence tomography. Results At baseline, metamorphopsia was detected in the vertical and/or horizontal directions in 29 (69.0%) eyes; the mean vertical and horizontal scores were 0.59 ± 0.57 and 0.52 ± 0.67, respectively. The maximum inner retinal thickness showed no association with the M-CHARTS score, but the M-CHARTS score was correlated with the total foveal thickness (r = 0.43, p = 0.004), the height of serous retinal detachment (r = 0.31, p = 0.047), and the maximum outer retinal thickness (r = 0.36, p = 0.020). One month after treatment, both the inner and outer retinal thickness substantially decreased. However, metamorphopsia persisted in 26 (89.7%) of 29 eyes. The posttreatment M-CHARTS score was not correlated with any posttreatment morphological parameters. However, the posttreatment M-CHARTS score was weakly correlated with the baseline total foveal thickness (r = 0.35. p = 0.024) and closely correlated with the baseline M-CHARTS score (r = 0.78, p < 0.001). Conclusions Metamorphopsia associated with acute BRVO was quantified using M-CHARTS. Initial microstructural changes in the outer retina from acute BRVO may primarily account for the metamorphopsia. |
| Databáze: | OpenAIRE |
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