Modified hamster atrial cardiac muscle cells isolated in the anterior chamber of the eye
| Autor: | John O. Oberpriller, Jean C. Oberpriller |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
medicine.medical_specialty
Time Factors Anterior Chamber Adipose tissue Connective tissue Biology Myofibrils Cricetinae Internal medicine medicine Animals Regeneration Transplantation Homologous Myocyte Heart Atria Molecular Biology Actin Mesocricetus Endoplasmic reticulum Cardiac muscle musculoskeletal system Transplantation Sarcoplasmic Reticulum medicine.anatomical_structure Endocrinology Heart Injuries sense organs Cardiology and Cardiovascular Medicine Myofibril |
| Zdroj: | Journal of Molecular and Cellular Cardiology. 9:1013-1017 |
| ISSN: | 0022-2828 |
| DOI: | 10.1016/s0022-2828(77)80053-9 |
| Popis: | Pieces of atria from young hamsters were transplanted into the anterior chamber of the eye and observed for morphological changes at 5, 10, 20, 30, 40 and 60 days after transplantation. During this period of observation, the transplant was vascularized and the number of myocytes decreased. After 20 days the cardiac muscle cells were usually seen in small clusters in between an increasing amount of connective tissue and fat cells. There was no indication of proliferative activity of myocytes in the grafts. The most striking change in myocyte ultrastructure, beginning at 5 days and continuing throughout to 60 days, was a change in myofibrillar structure and an increase in sarcoplasmic reticulum in many cardiac muscle cells. In these cardiac muscle cells, the Z material was thickened and had attached thin filaments, and often these complexes were scattered at random throughout the cell in association with an accumulation of sarcoplasmic reticulum. These observations are discussed in relation to other reports of similar Z band/thin filament complexes and adjacent sarcoplasmic reticulum. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|