Acute hepatitis m childhood: virological, immunological and clinical aspects
| Autor: | L Tucciarone, V Nastasi, S Mattia, M Manganaro, U. Bartmann, Giovanni Nigro, Andrea Torre, T. Perrone |
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| Rok vydání: | 1992 |
| Předmět: |
Male
Herpesvirus 4 Human Pediatrics medicine.medical_specialty Hepatitis Viral Human Congenital cytomegalovirus infection medicine.disease_cause Asymptomatic Virus medicine Humans Infectious Mononucleosis Child Pharmacology Hepatitis B virus Hepatitis biology business.industry Infant General Medicine Hepatitis B medicine.disease biology.organism_classification Hepadnaviridae Child Preschool Acute Disease Cytomegalovirus Infections Immunology Female medicine.symptom business Viral hepatitis |
| Zdroj: | Biomedicine & Pharmacotherapy. 46:155-160 |
| ISSN: | 0753-3322 |
| DOI: | 10.1016/0753-3322(92)90023-z |
| Popis: | Virological, immunological and clinical findings in 7 previously healthy children, aged 18 months to 11 years, with viral hepatitis are reported. Asymptomatic and fully recovering, although protracted, hepatitis B was diagnosed by chance in a 1 1 2 year-old boy. Anicteric and short-term hepatitis occurred in three children with Epstein-Barr virus infection, concomitantly with typical mononucleosis syndrome. On the contrary, cytomegalovirus (CMV)-associated hepatitis was severe and protracted in two children, and fatal in a 4-year-old girl, whose main autoptic finding was submassive hepatic necrosis. Therefore, our study showed that acute viral hepatitis in non-immunocompromised children is generally self-limited and that CMV hepatitis is more frequent and severe than commonly believed. pediatrie hepatitis / cytomegalovirus / Epstein-Barr virus / hepatitis B virus. |
| Databáze: | OpenAIRE |
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