Oral resveratrol supplementation improves Metabolic Syndrome features in obese patients submitted to a lifestyle-changing program
| Autor: | Gislaine Cândida Batista-Jorge, Deborah de Farias Lelis, Marise Fagundes Silveira, Sérgio Henrique Sousa Santos, Antônio Sérgio Barcala-Jorge, A. M. B. De Paula, André Luiz Sena Guimarães, João Marcus Oliveira Andrade |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 0301 basic medicine Tecido adiposo Polifenóis Administration Oral Physiology Resveratrol Placebo Exercícios físicos Fitonutrientes 030226 pharmacology & pharmacy General Biochemistry Genetics and Molecular Biology Placebos 03 medical and health sciences chemistry.chemical_compound Síndrome metabólica 0302 clinical medicine Diabetes mellitus medicine Humans Obesity General Pharmacology Toxicology and Pharmaceutics Life Style Metabolic Syndrome Creatinine business.industry Diabetes food and beverages General Medicine Middle Aged Anthropometry medicine.disease Lipids 030104 developmental biology Obesidade chemistry Dietary Supplements Female lipids (amino acids peptides and proteins) Metabolic syndrome Energy Metabolism business Body mass index |
| Zdroj: | Repositório Institucional da UFMG Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
| ISSN: | 0024-3205 |
| Popis: | CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Aims: the aim of the present study was to evaluate the oral resveratrol effects associated with diet and physical training changes on anthropometric and biochemical parameters. Main methods: 25 individuals aged from 30 to 60 years old; with Body Mass Index (BMI) ≥ 30 kg/m2 were included in the study. Following the primary evaluation (anthropometric and clinical), the patients were randomly divided into 2 groups: (1) Placebo: Physical activity program + Diet + Placebo; (2) Resveratrol: Physical activity program + Diet + Resveratrol (RVS) (250 mg/day) for three months. Anthropometric and biochemical parameters were evaluated at baseline and after the treatment period. Key findings: the main findings showed that the resveratrol supplementation improved total cholesterol (TC), High-density Lipoprotein cholesterol (HDL-c), Very-low density Lipoprotein cholesterol (VLDL-c), urea, creatinine and albumin serum levels. Significance: these findings indicate that this polyphenol may be an option to potentiate the beneficial effects induced by dietary and physical activity programs in the Metabolic Syndrome (MetS) treatment. |
| Databáze: | OpenAIRE |
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