Effects of underwater sound exposure on neurological function and brain histology
| Autor: | Florence M. Bareyre, Andrew N. Ritting, Helmut L. Laurer, Andrew B. Russ, Ramesh Raghupathi, Kathryn E. Saatman |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Acoustics and Ultrasonics Diving Central nervous system Biophysics Audiology pCO2 Cardiovascular Physiological Phenomena Sound exposure Central Nervous System Diseases Heart rate otorhinolaryngologic diseases Medicine Animals Radiology Nuclear Medicine and imaging Sound pressure Analysis of Variance Radiological and Ultrasound Technology business.industry Surgery Cardiovascular physiology Rats medicine.anatomical_structure Blood pressure Vestibular Diseases Arterial blood business Noise Psychomotor Performance |
| Zdroj: | Ultrasound in medicinebiology. 28(7) |
| ISSN: | 0301-5629 |
| Popis: | To evaluate the safety of sonar exposure from a neurological perspective, the vulnerability of the central nervous system to underwater exposure with high-intensity, low-frequency sound (HI-LFS) was experimentally examined. Physiological, behavioral and histological parameters were measured in anesthetized, ventilated rats exposed to brief (5 min), underwater HI-LFS. Exposure to 180 dB sound pressure level (SPL) re 1 microPa at 150 Hz (n = 9) did not alter acute cardiovascular physiology (arterial blood pH, pO(2), pCO(2), heart rate, or mean arterial blood pressure) from that found in controls (n = 11). Rats exposed to either 180 dB SPL re 1 microPa at 150 Hz (n = 12) or 194 dB SPL re 1 microPa at 250 Hz (n = 12) exhibited normal cognitive function at 8 and 9 days after sound exposure. Evaluation of neurological motor function revealed a minor deficit 7 days after 180 dB SPL/150 Hz exposure that resolved by 14 days, and no deficits after 194 dB SPL/250 Hz exposure. No overt histological damage was detected in any group. These data suggest that underwater HI-LFS exposure may cause transient, mild motor dysfunction. |
| Databáze: | OpenAIRE |
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