The Population Impact of Late Presentation With Advanced HIV Disease and Delayed Antiretroviral Therapy in Adults Receiving HIV Care in Latin America

Autor: Belaunzarán-Zamudio, P.F., Caro-Vega, Y.N., Shepherd, B.E., Rebeiro, P.F., Crabtree-Ramírez, B.E., Cortes, C.P., Grinsztejn, B., Gotuzzo Herencia, José Eduardo, Mejía Cordero, Fernando Alonso, Padgett, D., Pape, J.W., Rouzier, V., Veloso, V., Cardoso, S.W., McGowan, C.C., Sierra-Madero, J.G., Caribbean, Central and South America network for HIV epidemiology (CCASAnet)
Rok vydání: 2019
Předmět:
Adult
Male
Pediatrics
medicine.medical_specialty
Latin Americans
Epidemiology
Population
Marginal structural model
HIV Infections
Kaplan-Meier Estimate
Disease
purl.org/pe-repo/ocde/ford#3.03.09 [https]
acquired immune deficiency syndrome
Severity of Illness Index
Time-to-Treatment
03 medical and health sciences
Sex Factors
0302 clinical medicine
Risk Factors
medicine
Humans
030212 general & internal medicine
education
Retrospective Studies
Acquired Immunodeficiency Syndrome
education.field_of_study
030505 public health
business.industry
adult
Age Factors
Retrospective cohort study
Original Contribution
Middle Aged
HIV infection
Antiretroviral therapy
CD4 Lymphocyte Count
retrospective studies
Early Diagnosis
Latin America
Anti-Retroviral Agents
Attributable risk
Female
0305 other medical science
business
early diagnosis
Hiv disease
Zdroj: Am J Epidemiol
ISSN: 1476-6256
0002-9262
Popis: Late presentation to care and antiretroviral therapy (ART) initiation with advanced human immunodeficiency virus (HIV) disease are common in Latin America. We estimated the impact of these conditions on mortality in the region. We included adults enrolled during 2001-2014 at HIV care clinics. We estimated the adjusted attributable risk (AR) and population attributable fraction (PAF) for all-cause mortality of presentation to care with advanced HIV disease (advanced LP), ART initiation with advanced HIV disease, and not initiating ART. Advanced HIV disease was defined as CD4 of
Databáze: OpenAIRE