Serologic Screening for Herpes Simplex Virus Type 2 in Persons With Human Immunodeficiency Virus

Autor: Rhoda Ashley Morrow, Edward W. Hook, Nicholas Van Wagoner, Jeannette Y. Lee, Paula Dixon
Rok vydání: 2013
Předmět:
Zdroj: The American Journal of the Medical Sciences. 346:108-112
ISSN: 0002-9629
Popis: Screening for subclinical herpes simplex virus type 2 (HSV-2) may be a useful adjunct in human immunodeficiency virus (HIV) care. However, HSV-2 serological tests have been suggested to perform less well in HIV-infected populations. In this study, HerpeSelect HSV-2 ELISA was compared with the Sure-Vue Rapid HSV-2 Test for HSV-2 screening of sera from 310 HIV-infected persons receiving care at an HIV-dedicated clinic in the Southeastern United States. In the study, assay agreement and whether the performance of both tests, rather than 1 test alone, would improve screening accuracy were determined. Overall percent test agreement was 96%. Negative percent agreement was best at a HerpeSelect index value
Databáze: OpenAIRE