Venesection is an effective non-pharmacological treatment for patients with high serum ferritin type 2 diabetes
| Autor: | Erik W. Thompson, M. Shann Wilson |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism Type 2 diabetes lcsh:Diseases of the endocrine glands. Clinical endocrinology 03 medical and health sciences 0302 clinical medicine Endocrinology Pharmacotherapy Internal medicine Diabetes mellitus medicine 030212 general & internal medicine Pathological Non pharmacological lcsh:RC648-665 biology business.industry Insulin High serum medicine.disease Surgery Ferritin biology.protein business |
| Zdroj: | Journal of Clinical and Translational Endocrinology Case Reports, Vol 3, Iss, Pp 1-5 (2017) |
| ISSN: | 2214-6245 |
| DOI: | 10.1016/j.jecr.2016.10.002 |
| Popis: | Aims/Hypothesis Previous studies have associated serum ferritin levels with type 2 diabetes, so it's well recognised that there is a subset of patients with type 2 diabetes and also with elevated serum ferritin. The aim of this pilot study was to test whether venesection is a viable treatment option for patients with type 2 diabetes. Methods Four cases with elevated serum ferritin and type 2 diabetes were subjected to monthly venesection for 3–9 months, and monitored 3 monthly for serum ferritin and glycated haemoglobin (HbA1c). Results In all four cases, serum ferritin was dramatically reduced, and the HbA1c was reduced in all but one case, which was a diet-only controlled patient with diabetes and had near normal HbA1c. In two cases, HbA1c was reduced by 2–3% units (22–33 mmol/mol), making it superior to any current medication. Conclusions/Interpretation Venesection was used here successfully with oral pharmacotherapy, thereby avoiding the use of insulin. Findings of this study may provide clinicians a powerful new tool to intervene in the pathological process of type 2 diabetes by a very simple manoeuvre - venesection. These results need to be repeated and validated in a larger trial as a priority. |
| Databáze: | OpenAIRE |
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