Cannabidiol or CBD Oil: Help, Hope, and Hype for Psychiatric and Neurologic Conditions
| Autor: | David W. Newton, Marian Newton |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Drug
medicine.medical_specialty media_common.quotation_subject medicine.medical_treatment Cannabis sativa digestive system Food and drug administration Hope 03 medical and health sciences 0302 clinical medicine Health claims on food labels medicine Cannabidiol Humans Child Psychiatry Neuropharmacology Cannabis media_common biology Cannabinoids business.industry Mental Disorders biology.organism_classification digestive system diseases 030227 psychiatry surgical procedures operative Cannabinoid Nervous System Diseases Pshychiatric Mental Health business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of the American Psychiatric Nurses Association. 26:447-457 |
| ISSN: | 1532-5725 1078-3903 |
| DOI: | 10.1177/1078390320929410 |
| Popis: | OBJECTIVE: This article presents proven, promising, and potential therapeutic uses for cannabidiol (CBD) in the treatment of psychiatric and neurologic conditions and diseases. It presents popular, but scientifically unproven health and therapeutic claims of CBD supporting the beneficial homeostatic effects of the intrinsic or endogenous cannabinoid system. It includes a review of cannabinoid pharmacology; it compares properties and the legal status of CBD and THC (delta 9-tetrahydrocannabinol) as well as the hemp and marijuana varieties of Cannabis, and it reviews the historic 2018 U.S. Food and Drug Administration approval of Epidiolex, an oral solution of cannabidiol for two rare treatment-resistant childhood epilepsies, as the first Cannabis-derived drug. METHOD: We reviewed literature on cannabidiol, CBD, the endocannabinoid neuropharmacology system, and hemp and marijuana varieties of Cannabis sativa. RESULTS: The proven and promising medical uses and deficiencies of unproven health claims for CBD, legal implications for Cannabis-derived drugs, and comparisons of CBD and THC and hemp and marijuana are summarized objectively with pertinent references. CONCLUSION: CBD and CBD and THC combinations have potential to provide safe, effective therapy for several psychiatric and neurologic conditions and diseases. However, such achievement will require a uniform standard of CBD purity and strength, and corroboration from adequately large and rigorously controlled clinical research studies. |
| Databáze: | OpenAIRE |
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