The incidence and risk factors of gastrointestinal complications after hepatectomy: a retrospective observational study of 1329 consecutive patients in a single center
| Autor: | Wei-Feng Liu, Cai Li, Shi-Hong Wen, Ke-Xuan Liu, Bao-Chuan Li, Zhi-Qiu Xia |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood transfusion Adolescent Biliary Tract Diseases medicine.medical_treatment Single Center Young Adult Postoperative Complications Risk Factors medicine Hepatectomy Humans Child Aged Retrospective Studies Aged 80 and over Univariate analysis business.industry Incidence Liver Diseases Incidence (epidemiology) Retrospective cohort study Odds ratio Perioperative Length of Stay Middle Aged Surgery Elective Surgical Procedures Anesthesia population characteristics Female Morbidity business human activities |
| Zdroj: | Journal of Surgical Research. 192:440-446 |
| ISSN: | 0022-4804 |
| Popis: | Background: Despite of the importance of gastrointestinal (GI) complications in morbidity and mortality after major and moderate surgeries, it is not yet specifically studied in patients undergoing hepatectomy. This study was aimed to investigate the in-hospital incidence and potential risk factors of GI complications after open hepatectomy in our hospital. Subjects and methods: Prospectively recorded perioperative data from 1329 patients undergoing elective hepatectomy were retrospectively reviewed. The in-hospital incidence of GI complications was investigated, and independent risk factors were analyzed by multiple logistic regression. Results: GI complications occurrence was 46.4%. Univariate analysis showed that preoperative Child-Pugh score, total bilirubin, aspartate transaminase, anesthesia duration, operation duration, intraoperative blood loss, crystalloid and colloid infusion, blood transfusion, urine output, use of Pringle maneuver were statistically different between patients with and without GI complications (P < 0.05). Moreover, patients with GI complications had a more prolonged postoperative parenteral nutrient supporting time, hospital stay and ICU stay, and higher incidence of other complications than those without GI complications (P < 0.05). Multivariate regression indicated that long duration of anesthesia (odds ratio 2.51, P < 0.001) and use of Pringle maneuver (odds ratio 1.37, P ¼ 0.007) were independent risk factors of GI complications after hepatectomy. Conclusions: The incidence of GI complications after hepatectomy is high, which is related to an increase of other complications and a prolonged hospital stay. Avoidance of routinely use of Pringle maneuver and shortening the duration of anesthesia are important measures to reduce the postoperative GI complications. |
| Databáze: | OpenAIRE |
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