Clinical relevance of diffusion tensor imaging parameters in lumbar disco-radicular conflict
| Autor: | A. Hess, Ahmed Larbi, E. Schouman-Claeys, J. Lincot, François Cornelis, B. Dallaudière, Anne Cotten, Jean-Pierre Laissy, V. Balbi |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Sacrum Nerve root Sensitivity and Specificity Cohort Studies Lumbar Imaging Three-Dimensional Fractional anisotropy Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Discoradicular conflict Prospective Studies Aged Aged 80 and over Observer Variation Lumbar Nerve Lumbar Vertebrae Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Echo-Planar Imaging Nerve Compression Syndromes Magnetic resonance imaging General Medicine Middle Aged Image Enhancement Sagittal plane Spine Surgery medicine.anatomical_structure Diffusion tensor imaging Diffusion Magnetic Resonance Imaging Female Nuclear medicine business Spinal Nerve Roots Tractography Intervertebral Disc Displacement Diffusion MRI |
| Zdroj: | Diagnostic and interventional imaging. 95(1) |
| ISSN: | 2211-5684 |
| Popis: | Purpose To measure the fractional anisotropy (FA) and the mean diffusivity (MD) values of L4, L5 and S1 nerve roots using diffusion tensor imaging (DTI) and to correlate them with four different clinical patterns. Patients and methods Fifty-six human participants were prospectively included and divided between four groups: healthy subjects, patients with clinical symptomatic nerve root pain with and without anatomical discoradicular conflict and patients with incidental anatomical discoradicular conflict seen on magnetic resonance imaging (MRI). MRI protocol included anatomical sequences (sagittal T1- and T2-weighted, axial T2-weighted) and a 25 directions DTI sequence. FA and MD values were measured in consensus by two readers and compared between the four groups. Results Mean FA and MD values were significantly different for patients with clinically symptomatic nerve root pain (n = 27) both with (n = 16) (FA = 0.187 ± 0.015; MD = 510 ± 40) and without (n = 11) (FA = 0.193 ± 0.011; MD = 490 ± 30.5) anatomical discoradicular conflict compared to healthy subjects (n = 29) (FA = 0.221 ± 0.011; MD = 460.9 ± 35.5) including 2 subjects with incidental anatomical discoradicular conflict (FA = 0.211 ± 0.013; MD = 450.8 ± 41.2) on MRI (P = 0.003). Conclusion Measurement of FA and MD values of L4, L5 and S1 nerve roots using DTI could be useful in lumbar nerve root pain assessment. Further studies with different image processing methods are needed. |
| Databáze: | OpenAIRE |
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