Influence of low grade exercise on skeletal scintigraphy using Tc-99m methylene diphosphonate
| Autor: | Maha Abd El-Kareem, Amr Amin, Abu Baker Yahia |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.diagnostic_test Technetium Tc 99m Medronate business.industry Significant difference Soft tissue General Medicine Middle Aged Scintigraphy Bone and Bones Highly sensitive Femoral diaphysis medicine Humans Tc-99m Methylene Diphosphonate Female Radiology Nuclear Medicine and imaging Treadmill Radionuclide Imaging Nuclear medicine business Exercise |
| Zdroj: | Nuclear Medicine Review. 18:61-64 |
| ISSN: | 1644-4345 1506-9680 |
| DOI: | 10.5603/nmr.2015.0016 |
| Popis: | Background Tc-99m methylene diphosphonate [MDP] bone scan is the basis of the skeletal imaging in nuclear medicine being a highly sensitive tool for detecting bone diseases. Mechanical stimulation induced by low grade exercise or whole-body vibration appears to be advantageous regarding the maintenance and/or improvement of skeletal mass in humans. We aimed to assess the physiological influence of low grade exercise on the quality of skeletal scintigraphy using Tc-99m MDP. Material and methods Tc-99m MDP bone scan was done for 92 volunteers [Group 1; G1]. Five days later, the same subjects were re-scanned [Group 2; G2] after an exercise on treadmill for 5 minutes. Image quality was assessed using quantitative measures whereby equal regions of interest (ROI) were drawn over the femoral diaphysis, and the contralateral adductor area. The total number of counts from the bone [B] ROI and soft tissue [ST] ROI was expressed as a ratio [B:ST ratio] and a mean value for each was established. Results Statistically significant difference was found between the B:ST ratio means [p = 0.001] in G1 and G2. Conclusion This study raised a physiological influence of low grade exercise on the image quality of tc-99m MDP skeletal scintigraphy by increasing MDP osseous uptake. |
| Databáze: | OpenAIRE |
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