Anti-inflammatory activity of Anthemis tricolor Boiss
| Autor: | Bijen Kivçak, Özge Özçınar, Serkan Demirkan |
|---|---|
| Přispěvatelé: | Ege Üniversitesi, Kırıkkale Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
sesquiterpene
Erythema medicine.drug_class Negative control Anthemis tricolor Dermatology Sesquiterpene Anti-inflammatory n-hexane 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Stomach ache Immunology and Allergy Medicine Anthemis anti-inflammatory Original Paper Traditional medicine biology business.industry biology.organism_classification chemistry Betamethasone minimal erythema dose medicine.symptom business medicine.drug |
| Zdroj: | Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii |
| Popis: | WOS: 000506827300006 PubMed: 31997994 Introduction: Traditionally, Anthemis genus has been used for the treatment of gastrointestinal disorders, haemorrhoid and stomach ache in Europe. There are several in-vitro and in-vivo studies that showed the pharmacological properties of Anthemis species such as antibacterial, anti-inflammatory, antiedemic and hepatoprotective properties. Aim: Our study referred to the model of inflammation formed in rats; we aimed to evaluate anti-inflammatory properties of A. tricolor extracts. Material and methods: Five different extracts of A. tricolor were tested against the negative control and 2 different topical corticosteroids (betamethasone and hydrocortisone); n-hexane and sesquiterpene extracts of A. tricolor Bois showed significantly reduced erythema compared to the negative control. Results: Only n-hexane and sesquiterpene extracts of A. tricolor have the anti-inflammatory effect. Conclusions: This is the first report on anti-inflammatory activity of A. tricolor and we showed an anti-inflammatory effect of n-hexane and sesquiterpene extract of A. tricolor with UV erythema test as a_result, hence A. tricolor extracts can be used for the treatment of inflammatory skin diseases due to anti-inflammatory activity. |
| Databáze: | OpenAIRE |
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