Etiology and Risk Factors for Infectious Keratitis in South Texas
| Autor: | Madeleine Puig, Ricardo Salinas, Menachem Weiss, Ahmad Kheirkhah, Daniel A. Johnson |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Microbiological culture Acanthamoeba Infectious Keratitis Keratitis 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Medicine Fungal keratitis Corneal Ulcer Fungus biology Bacteria business.industry biology.organism_classification medicine.disease corneal ulcer Dermatology Contact lens Ophthalmology Acanthamoeba keratitis lcsh:RE1-994 030221 ophthalmology & optometry Original Article business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Ophthalmic & Vision Research Journal of Ophthalmic & Vision Research, Vol 15, Pp 128-137 (2020) |
| ISSN: | 2008-2010 |
| Popis: | Purpose: To determine the causative organisms and associated risk factors for infectious keratitis in South Texas. Methods: This retrospective study was performed at a tertiary teaching hospital system in South Texas. Medical records of all patients who presented with infectious keratitis from 2012 to 2018 were reviewed. Only patients with culture-proven bacterial, fungal, and Acanthamoeba keratitis were included. Results: In total, 182 eyes of 181 patients had culture-proven bacterial, fungal, or Acanthamoeba keratitis. The age of patients ranged from 3 to 93 years, with a mean of 48.3 ± 20.8 years. The most common etiologic agent was bacteria, with 173 bacterial cultures (95.1%) recovered, followed by 13 fungal cultures (7.1%), and 3 Acanthamoeba cultures (1.6%). Of the 218 bacterial isolates, coagulase-negative Staphylococcus was the most common (25.7%), followed by Pseudomonas aeruginosa (23.4%), Staphylococcus aureus (11.0%), and Moraxella (7.8%). Fusarium was the most common fungal isolate (46.2%). The most common risk factors for infectious keratitis included contact lens wear (32.4%), underlying corneal disease (17.6%), trauma (14.3%), and ocular surface disease (13.7%). Conclusions: Bacteria are the most common cause of infectious keratitis in this patient population, with coagulase-negative Staphylococcus and Pseudomonas as the most common isolates. The prevalence of culture-positive fungal keratitis is significantly lower than that of bacterial keratitis. Contact lens wear is the most common risk factor associated with infectious keratitis in South Texas. |
| Databáze: | OpenAIRE |
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