Diagnostic value of tumor-fascia relationship in superficial soft tissue masses on magnetic resonance imaging

Autor: Masatugu Takami, Makoto Ieguchi, Hiroaki Nakamura, Masanari Aono, Naoto Oebisu, Manabu Hoshi, Tadashi Iwai
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Soft Tissue Neoplasms
Pathology and Laboratory Medicine
030218 nuclear medicine & medical imaging
Diagnostic Radiology
0302 clinical medicine
Subcutaneous Tissue
Edema
Medicine and Health Sciences
Fascia
Child
Aged
80 and over
Univariate analysis
Multidisciplinary
medicine.diagnostic_test
Radiology and Imaging
Sarcomas
Soft tissue
Middle Aged
Magnetic Resonance Imaging
Immunohistochemistry
Tumor Burden
medicine.anatomical_structure
Oncology
030220 oncology & carcinogenesis
Child
Preschool
Medicine
Female
Radiology
Sarcoma
medicine.symptom
Anatomy
Research Article
Adult
medicine.medical_specialty
Soft Tissues
Adolescent
Imaging Techniques
Science
Malignancy
Research and Analysis Methods
Diagnosis
Differential
03 medical and health sciences
Young Adult
Malignant Tumors
Signs and Symptoms
Diagnostic Medicine
medicine
Cancer Detection and Diagnosis
Humans
Benign Tumors
Aged
Retrospective Studies
business.industry
Cancers and Neoplasms
Biology and Life Sciences
Infant
Magnetic resonance imaging
medicine.disease
Biological Tissue
Metastatic Tumors
business
Zdroj: PLoS ONE
PLoS ONE, Vol 13, Iss 12, p e0209642 (2018)
ISSN: 1932-6203
Popis: PurposeMany surgeons participate in the management of superficial soft tissue masses, and a preoperative incorrect diagnosis frequently results in dismal oncological outcomes. The aim of this study was to identify distinguishing magnetic resonance imaging features between malignant and non-malignant lesions.MethodsThe clinicopathological data for 219 patients (men 114; women 105) with superficial soft tissue masses treated from January 2007 to December 2016 in our institution were retrospectively analyzed. The median age at the first visit was 55.6 years (range 1-90 years). MRI findings of tumor size, margin, lobulation, intratumoral hemorrhage, peritumoral edema, and tumor-fascia relationship were compared with the final histological diagnosis and tumor grade.ResultsUnivariate analysis revealed significant relationships between histologically malignant lesions and tumor size ≥5 cm (p = 0.035), positive peritumoral edema (p = 0.031), and tumor-fascia relationship (pConclusionsTumors measuring ≥5 cm and the tumor-fascia relationship on magnetic resonance imaging are highly indicative of malignancy. When superficial soft tissue masses cross the superficial fascia and form obtuse angles with the fascia, sarcoma should be considered. The tumor-fascia relationship can offer surgeons useful information regarding the status of superficial soft tissue masses.
Databáze: OpenAIRE
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