Incidence and Risk Factors for Postpartum Severe Hypertension in Women with Underlying Chronic Hypertension
| Autor: | Alan T.N. Tita, Angelica V. Glover, Lorie M. Harper, Sarah Anderson, Joseph R. Biggio |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Logistic regression 03 medical and health sciences 0302 clinical medicine Pre-Eclampsia Interquartile range Pregnancy Risk Factors medicine Humans Chronic hypertension Retrospective Studies 030219 obstetrics & reproductive medicine Obstetrics business.industry Incidence (epidemiology) Incidence Obstetrics and Gynecology Retrospective cohort study Puerperal Disorders medicine.disease Logistic Models ROC Curve Pediatrics Perinatology and Child Health Cohort Chronic Disease Hypertension Female business Time to diagnosis |
| Zdroj: | American journal of perinatology. 36(7) |
| ISSN: | 1098-8785 |
| Popis: | Objective To determine risk factors and time to diagnosis of postpartum severe hypertension (PHTN) in women with chronic hypertension (CHTN). Study Design Retrospective cohort of singleton pregnancies with CHTN at a tertiary care center. The primary outcome was PHTN, defined as hypertension ≥160/ ≥ 110 mm Hg during an emergency room (ER) or outpatient visit, or hospitalization within 8 weeks postpartum. Multivariable logistic regression was used to assess independent risk factors for PHTN. Results Two-hundred thirty-five women had CHTN: 30 (12.8%) were diagnosed with PHTN, and 17 (7.2%) were hospitalized or seen in the ER for PHTN. Women with PHTN had more severe superimposed pre-eclampsia (p 135 mm Hg (aOR 4.55, 95% CI, 1.64–12.61) at discharge remained independently associated with PHTN. Median time to diagnosis of PHTN was 10 days (interquartile range [IQR] 6–32 days); time to diagnosis among women requiring readmission or ER evaluation was 8 days (IQR 5–11 days). Conclusion PHTN occurred in 13% of women with CHTN, and was associated with blood pressure level and number of medications at discharge. |
| Databáze: | OpenAIRE |
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