Strategies by which some pathogenic trichomonads integrate diverse signals in the decision-making process
| Autor: | Costa e Silva Filho F, Arroyo R, Braga Mb, López Lb, López Jo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2000 |
| Předmět: |
Male
Iron Cell Integrin Trichomonas Infections Urogenital System Virulence Tritrichomonas foetus Biology medicine.disease_cause Host-Parasite Interactions Microbiology trichomonal virulence medicine Extracellular Trichomonas vaginalis Animals Humans parasitic protozoa lcsh:Science Cytotoxicity Multidisciplinary host-cell parasite interaction relationships Epithelial Cells biology.organism_classification Extracellular Matrix Bacterial adhesin medicine.anatomical_structure Trichomonas biology.protein Female lcsh:Q Signal Transduction |
| Zdroj: | Anais da Academia Brasileira de Ciências, Volume: 72, Issue: 2, Pages: 173-186, Published: JUN 2000 Anais da Academia Brasileira de Ciências, Vol 72, Iss 2, Pp 173-186 (2000) Anais da Academia Brasileira de Ciências v.72 n.2 2000 Anais da Academia Brasileira de Ciências Academia Brasileira de Ciências (ABC) instacron:ABC |
| Popis: | The interaction between each one of Trichomonas vaginalis and Tritrichomonas foetus with their hosts is a complex process in which components associated to the cell surfaces of both parasites and host epithelial cells, and also to soluble components found in vaginal/urethral secretions, are involved. Either cytoadhesion or the cytotoxicity exerted by parasites to host cells can be dictated by virulence factors such as adhesins, cysteine proteinases, laminin-binding proteins, integrins, integrin-like molecules, a cell detachment factor, a pore-forming protein, and glycosidases among others. How trichomonads manipulate informations from the extracellular medium, transduce such informations, and respond to them by stimulating the activities of some surface molecules and/or releasing enzymes are the aspects concerning trichomonal virulence which are here briefly reviewed and discussed. |
| Databáze: | OpenAIRE |
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