Sarcoidosis Presenting with Diabetes Insipidus Followed by Acute Cranial Nerve Syndrome
| Autor: | Willem Luyendijk, Hans G. Koster, Peter F. Bruning, Ruben E. M. Hekster |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty Adolescent Sarcoidosis medicine.medical_treatment Basal (phylogenetics) Meningoencephalitis Biopsy Internal Medicine medicine Humans Pituitary Neoplasms Craniotomy Pituitary stalk Brain Diseases medicine.diagnostic_test business.industry Cranial nerves Cranial Nerves Peripheral Nervous System Diseases medicine.disease Surgery Diabetes insipidus Female business Diabetes Insipidus |
| Zdroj: | Acta Medica Scandinavica. 205:441-444 |
| ISSN: | 0001-6101 |
| Popis: | Diabetes insipidus in a previously healthy 16-year-old girl led to surgical exploration of a pituitary stalk intumescence detected by oxygen cisternography with the use of tomography. Biopsy of the pituitary stalk contained chronically inflamed brain tissue. Subsequent liver and bone biopsies showed characteristic granulomata, confirming the diagnosis of sarcoidosis. Subfrontal craniotomy was followed by a rapidly progressive basal meningoencephalitis with multiple cranial nerve involvement. The need to establish a causal diagnosis in diabetes insipidus is stressed. The rarity of the disorder and the presumed role of subfrontal craniotomy with regard to the flare-up of the sarcoidosis of the brain are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|