Determination of aflatoxins in milk sample with ionic liquid modified magnetic zeolitic imidazolate frameworks
| Autor: | Wu Yiqiu, Gao Shiqian, Siyuan Xie, Zhanen Zhang, Yan Yumeng, Xiumin Bao, Shao Zichun, Junxia Wang, Youyi Wu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Clinical Biochemistry
Mass spectrometry 030226 pharmacology & pharmacy 01 natural sciences Biochemistry Analytical Chemistry 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Adsorption Aflatoxins Limit of Detection Tandem Mass Spectrometry Desorption Imidazolate Animals Solid phase extraction Magnetite Nanoparticles Chromatography High Pressure Liquid Chromatography Solid Phase Extraction 010401 analytical chemistry Extraction (chemistry) Imidazoles Reproducibility of Results Cell Biology General Medicine 0104 chemical sciences Milk chemistry Ionic liquid Linear Models Zeolites Zeolitic imidazolate framework |
| Zdroj: | Journal of Chromatography B. 1128:121778 |
| ISSN: | 1570-0232 |
| Popis: | The ionic liquid (IL) was introduced to the synthesis system of magnetic zeolite imidazolate framework-8 (M/ZIF-8), which was benefit to the formation of binary imidazole and the co-modification of M/ZIF-8. The morphology and textural properties of ILM/ZIF-8 were characterized by SEM, TEM, BET and BJH. The crystal structural shape and size of MZIF-8 was unvaried with the interventional of IL. The ILM/ZIF-8 was applied to the concentration and determination of aflaoxins (AFB1, AFB2, AFG1 and AFG2) in milk samples based on magnetic solid phase extraction (MSPE) coupled with ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). The experimental parameters of the MSPE, including amount of ILM/ZIF-8, pH, type and amount of desorption solvent, extraction time and sample volume were investigated by a univariate method and orthogonal screening. The four AFs were concentrated from the 20 mL milk when 90 mg ILM/ZIF-8 was used as magnetic adsorbent. The extraction efficiency of AFs was higher than 80.0% within 15 min. The limits of quantitative and detection were 7.5–26.7 and 2.3–8.1 ng/L, respectively. The proposed method was applied to the determination of milk samples containing trace amounts of AFs and the recoveries ranged from 79.0% to 102.5%, with RSD below 7.7%. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect