Severe Histiolymphocytic and Heterophilic Bronchopneumonia as a Reaction to In Ovo Fowlpox Vaccination in Broiler Chicks
| Autor: | James A Smith, Maricarmen García, Charles L. Hofacre, Matti Kiupel, D. Brinson, Susan M. Williams |
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| Rok vydání: | 2010 |
| Předmět: |
Fowlpox
Pathology medicine.medical_specialty animal structures Biology In ovo Polymerase Chain Reaction Virus Parenchyma Bronchopneumonia medicine Animals Lymphocytes Lung Poultry Diseases Ovum Fowlpox virus General Veterinary Macrophages Viral Vaccine Viral Vaccines medicine.disease Virology Vaccination medicine.anatomical_structure embryonic structures Chickens |
| Zdroj: | Veterinary Pathology. 47:177-180 |
| ISSN: | 1544-2217 0300-9858 |
| DOI: | 10.1177/0300985809353314 |
| Popis: | Broiler chickens on several farms from a single poultry company experienced neurological signs and mortality in chicks between 3 days and 10 days of age over a 3-week period after use of a fowlpox-vectored infectious laryngotracheitis virus vaccine in ovo. At necropsy the lungs contained numerous tan or gray, opaque to translucent, 0.5- to 2.0-mm nodules in the parenchyma. Microscopic lesions were a multifocal severe lymphohistiocytic and heterophilic bronchopneumonia. Immunohistochemistry was positive for fowlpox virus in macrophages and lymphocytes, and polymerase chain reaction on paraffin-embedded lung tissues was positive for a fowlpox vector virus commonly used as a vaccine. The cause of the neurological signs was not determined. |
| Databáze: | OpenAIRE |
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