Assessment of a 10-year dog deworming programme on the transmission of Echinococcus multilocularis in Tibetan communities in Sichuan Province, China
| Autor: | Yan Huang, Danbazeli, Ke-Jun Xu, Qian Wang, Qi Wang, Sha Liao, Christine M. Budke, Renxing Yao, Chen Fan, Philip S. Craig, Fei Xie, Wei He, Bo Zhong, Zhang Guangjia, Patrick Giraudoux, Wen-Jie Yu, Liu Yang, Li Ruirui |
|---|---|
| Přispěvatelé: | Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty China 030231 tropical medicine Alveolar echinococcosis Echinococcus multilocularis Tibet Deworming 03 medical and health sciences 0302 clinical medicine Dogs Echinococcosis Environmental health Epidemiology medicine Prevalence Animals Dog Diseases [SDV.EE]Life Sciences [q-bio]/Ecology environment biology Transmission (medicine) Public health biology.organism_classification 3. Good health Praziquantel 030104 developmental biology Infectious Diseases 13. Climate action Parasitology [SDE.BE]Environmental Sciences/Biodiversity and Ecology medicine.drug |
| Zdroj: | International Journal for Parasitology International Journal for Parasitology, Elsevier, 2020, ⟨10.1016/j.ijpara.2020.08.010⟩ |
| ISSN: | 0020-7519 |
| Popis: | International audience; Human alveolar echinococcosis (AE) is considered a neglected zoonotic disease by the World Health Organization (WHO). The causative pathogen, Echinococcus multilocularis, lives as an adult tapeworm in the intestinal tract of canines. AE was identified as an emerging public health issue in Tibetan communities of Shiqu County 20 years ago. On St. Lawrence Island, Alaska (USA), in the 1980s peri-domestic transmission of E. multilocularis was controlled by regular deworming of owned dogs over a 10-year period. In Tibetan communities, on the Tibetan Plateau, control of E. multilocularis transmission is challenging due to the continental setting, complex epidemiology, disease ecology, geography, and socio-cultural factors. However, a control programme based on deworming owned dogs using praziquental (PZQ) has been carried out since 2006. Assessment was conducted in townships where baseline data were available 10 years prior. Purging of dogs by oral administration of arecoline was used to measure E. multilocularis prevalence, trapping small mammals around communities was employed to assess the change in infection of pikas and voles, and analyis of human AE abdominal ultrasound-based data was used to understand the change in prevalence in the past decade. After 10 years (2006-2016) of deworming owned dogs (definitive host) to control the disease, assessment was conducted in townships where baseline data were available. In all three evaluated townships, the E. multilocularis prevalence in owned dogs was significantly (P |
| Databáze: | OpenAIRE |
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