Lobular panniculitis: A manifestation of pancreatic tumor with fatal outcome
| Autor: | Marina Jovanović, Zoran Golušin, Kosta Petrovic, Nada Vuckovic, Slavica Sotirovic-Senicar, Aleksandra Petrović, Silvija Brkić |
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| Rok vydání: | 2005 |
| Předmět: |
Pathology
medicine.medical_specialty Necrosis Pancreatic disease fatal outcome lcsh:RC254-282 Pancreatic tumor Pathognomonic medicine Fat necrosis medicine.diagnostic_test business.industry pancreatic neoplasms Histology Hematology lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease lobular panniculitis Occult Oncology tumor markers Skin biopsy medicine.symptom fat necrosis business biological |
| Zdroj: | Archive of Oncology, Vol 13, Iss 3-4, Pp 153-155 (2005) |
| ISSN: | 1450-9520 0354-7310 |
| DOI: | 10.2298/aoo0504153j |
| Popis: | Lobular panniculitis is a skin condition that may be the first sign of underlying pancreatic disease. Though rare, the condition has been sufficiently well defined and pathognomonic, thus making differentiation from idiopathic lobular panniculitis quite possible. A 77-year-old woman was in apparently good general health condition when developed skin lesions in a form of erythematous painful fluctuant nodules localized predominantly on the breast, but also present on the arms, thighs, and trunk. Her serum and urinary amylase levels were respectively 3 and 8 fold higher than normal. On histology, skin biopsy showed acute lobular panniculitis with large foci of adipocyte necrosis. Examination of the breast excluded any specific process other than nodular subcutaneous inflammation, but revealed a tumor of the pancreatic head. The nodules spontaneously ulcerated exuding an oily thick brownish material. Her condition deteriorated, and she became progressively debilitated. The patient died before operation, within the next 3 weeks. Subcutaneous fat necrosis was the first manifestation of an otherwise occult pancreatic disease with fatal outcome. |
| Databáze: | OpenAIRE |
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