Evaluations of treatment efficacy of depression from perspective of both patients' symptoms and general sense of mental health and wellbeing: A large scale, multi-centered, longitudinal study in China
| Autor: | Yifeng Xu, Sai Zuo, Weichun Wang, Linda K. Byrne, Yiru Fang, Marita P. McCabe, David Mellor, Qingzhi Zeng |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Longitudinal study China Symptom 03 medical and health sciences 0302 clinical medicine Rating scale Outcome Assessment Health Care Hamilton Rating Scale for Depression (HRSD-17) medicine Humans Longitudinal Studies Psychiatry Biological Psychiatry Depression (differential diagnoses) Aged Depressive Disorder Wellbeing Perspective (graphical) Hamilton Rating Scale for Depression Middle Aged Mental health 030227 psychiatry Patient Outcome Assessment Psychiatry and Mental health Mood Observational design Remission Evaluation and Mood Inventory Tool (REMIT) Observational study Female Psychology 030217 neurology & neurosurgery Clinical psychology |
| Popis: | Relying on the absence, presence of level of symptomatology may not provide an adequate indication of the effects of treatment for depression, nor sufficient information for the development of treatment plans that meet patients' needs. Using a prospective, multi-centered, and observational design, the present study surveyed a large sample of outpatients with depression in China (n=9855). The 17-item Hamilton Rating Scale for Depression (HRSD-17) and the Remission Evaluation and Mood Inventory Tool (REMIT) were administered at baseline, two weeks later and 4 weeks, to assess patients' self-reported symptoms and general sense of mental health and wellbeing. Of 9855 outpatients, 91.3% were diagnosed as experiencing moderate to severe depression. The patients reported significant improvement over time on both depressive symptoms and general sense after 4-week treatment. The effect sizes of change in general sense were lower than those in symptoms at both two week and four week follow-up. Treatment effects on both general sense and depressive symptomatology were associated with demographic and clinical factors. The findings indicate that a focus on both general sense of mental health and wellbeing in addition to depressive symptomatology will provide clinicians, researchers and patients themselves with a broader perspective of the status of patients. |
| Databáze: | OpenAIRE |
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