Efficiency of Intermittent Exercise on Adiposity and Fatty Liver in Rats Fed With High-fat Diet
| Autor: | Nadia Carla Cheik, Flavia Regina Rodrigues Scarmagnani, Ana Raimunda Dâmaso, Marcela Sene-Fiorese, Eliseu A. Rossi, Ana Carolina Oliveira Duarte, Fernanda Duarte, Keico Okino Nonaka, Marla Simone Jovenasso Manzoni |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Physical Exertion Medicine (miscellaneous) Adipose tissue Weight Gain Eating Endocrinology Internal medicine Brown adipose tissue medicine Animals Rats Wistar Muscle Skeletal Adiposity Nutrition and Dietetics medicine.diagnostic_test business.industry Lipogenesis Fatty liver medicine.disease Dietary Fats Lipids Obesity Exercise Therapy Rats Fatty Liver Disease Models Animal medicine.anatomical_structure Adipose Tissue Liver medicine.symptom Energy Intake business Lipid profile Weight gain Lipoprotein |
| Zdroj: | Obesity. 16:2217-2222 |
| ISSN: | 1930-7381 |
| DOI: | 10.1038/oby.2008.339 |
| Popis: | Objective: This study aimed to examine and compare the effects of continuous or intermittent exercises on adiposity and fatty liver in rats fed with high-fat diet. Methods and Procedures: Wistar rats were divided according to diet composition—chow diet (C) or high-fat diet (H)—and kinds of exercise—sedentary (S), continuous (CE), or intermittent (IE) exercises. The CE group swam 90 min/day, and the IE group swam 3 × 30 min/day (at 4-h intervals between sessions); both groups exercised 5 days/week during 8 weeks. Body weight and food intake were recorded daily. Lipogenesis rate in vivo was determined by the incorporation of 3H2O into saponified lipids in retroperitoneal (RET), epididymal (EPI), and visceral (VIS) white adipose tissues, brown adipose tissue (BAT), liver (L), and gastrocnemius muscle (GAST) using the gravimetric method. Total cholesterol, high-density lipoprotein (HDL)-cholesterol, and triacylglycerol (TG) were analyzed. Results: The major finding of this study is that IE was more efficient than CE in reducing the adverse effects of high-fat diet and sedentarism. There was an improvement in the lipid profile and a reduction in food intake, body weight gain, visceral and central adiposity, and fatty liver, contributing to the control of obesity and other comorbidities, including nonalcoholic fat liver diseases. Discussion: Earlier studies have discussed the effects of diet consumption on adiposity and their relation to chronic diseases and obesity. This study discusses the effects of high-fat diet consumption and the different kinds of exercise on weight gain, adiposity, fatty liver, and lipid profile in rats. The results may depend on the exercise, time of each session, age, gender, and experimental period. |
| Databáze: | OpenAIRE |
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