Cloning and Heterologous Expression of the Thioviridamide Biosynthesis Gene Cluster from Streptomyces olivoviridis
| Autor: | Yoichi Hayakawa, Masumi Izawa, Takashi Kawasaki |
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| Rok vydání: | 2013 |
| Předmět: |
DNA
Bacterial Sequence analysis Molecular Sequence Data Heterologous Genetics and Molecular Biology Biology Peptides Cyclic Applied Microbiology and Biotechnology DNA sequencing Gene cluster Cloning Molecular Gene Cloning Regulation of gene expression Genetics Ecology Gene Expression Regulation Bacterial Sequence Analysis DNA Anti-Bacterial Agents Thioamides Genes Bacterial Multigene Family Streptomyces lividans Heterologous expression Food Science Biotechnology |
| Zdroj: | Applied and Environmental Microbiology. 79:7110-7113 |
| ISSN: | 1098-5336 0099-2240 |
| Popis: | Thioviridamide is a unique peptide antibiotic containing five thioamide bonds from Streptomyces olivoviridis . Draft genome sequencing revealed a gene (the tvaA gene) encoding the thioviridamide precursor peptide. The thioviridamide biosynthesis gene cluster was identified by heterologous production of thioviridamide in Streptomyces lividans . |
| Databáze: | OpenAIRE |
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