Influence of sample return time and ambient temperature on the performance of an immunochemical faecal occult blood test with a new buffer for colorectal cancer screening
| Autor: | Jeanne-Marie Bidan, Sylvain Manfredi, Samia Hamza, Côme Lepage, Jean Faivre, Vincent Dancourt, Antoine Drouillard |
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| Přispěvatelé: | Registre Bourguignon des Cancers Digestifs, Lipides - Nutrition - Cancer (U866) ( LNC ), Université de Bourgogne ( UB ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Ecole Nationale Supérieure de Biologie Appliquée à la Nutrition et à l'Alimentation de Dijon ( ENSBANA ) -Université de Bourgogne ( UB ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Ecole Nationale Supérieure de Biologie Appliquée à la Nutrition et à l'Alimentation de Dijon ( ENSBANA ) -Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand ( CHU Dijon ), Association de dépistage des cancers en Côte-d'Or (ADECA 21) ( ADECA 21 ), Mutualité française, Laboratoire du Centre d'examens de santé de la CPAM de Côte-d'Or ( Lab CES CPAM Dijon ), Caisse Primaire de l'Assurance Maladie ( CPAM ), Lipides - Nutrition - Cancer (U866) (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Ecole Nationale Supérieure de Biologie Appliquée à la Nutrition et à l'Alimentation de Dijon (ENSBANA)-Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Ecole Nationale Supérieure de Biologie Appliquée à la Nutrition et à l'Alimentation de Dijon (ENSBANA)-Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Association de dépistage des cancers en Côte-d'Or (ADECA 21) (ADECA 21), Laboratoire du Centre d'examens de santé de la CPAM de Côte-d'Or (Lab CES CPAM Dijon), Caisse primaire d'assurance maladie (CPAM) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Cancer Research Multivariate analysis Time Factors Epidemiology Colorectal cancer MESH: Reagent Kits Diagnostic MESH : Aged MESH : Hemoglobins MESH : Early Detection of Cancer [ SDV.CAN ] Life Sciences [q-bio]/Cancer Return time Screening programme Immunoenzyme Techniques Hemoglobins MESH : Specimen Handling MESH : Female MESH : Neoplasm Staging MESH : Reagent Kits Diagnostic MESH : Temperature Early Detection of Cancer MESH: Aged MESH: Middle Aged MESH : Prognosis Temperature MESH: Follow-Up Studies MESH: Neoplasm Staging Middle Aged Prognosis Predictive value MESH: Temperature MESH: Hemoglobins MESH : Occult Blood Oncology Colorectal cancer screening Occult Blood Female Seasons MESH : Colorectal Neoplasms Colorectal Neoplasms MESH : Time Factors Adenoma medicine.medical_specialty Sample (material) MESH : Male [SDV.CAN]Life Sciences [q-bio]/Cancer MESH: Prognosis Specimen Handling Animal science MESH : Immunoenzyme Techniques medicine Humans MESH: Early Detection of Cancer MESH : Middle Aged MESH: Specimen Handling MESH: Immunoenzyme Techniques Aged Neoplasm Staging MESH: Adenoma MESH: Humans MESH : Seasons business.industry MESH: Time Factors MESH : Humans Public Health Environmental and Occupational Health MESH : Follow-Up Studies medicine.disease MESH: Male Surgery MESH : Adenoma Reagent Kits Diagnostic Faecal occult blood test business MESH: Occult Blood MESH: Female MESH: Seasons MESH: Colorectal Neoplasms Follow-Up Studies |
| Zdroj: | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2016, 25 (2), pp.109-14. 〈http://journals.lww.com/eurjcancerprev/Abstract/2016/03000/Influence_of_sample_return_time_and_ambient.3.aspx〉. 〈10.1097/CEJ.0000000000000153〉 European Journal of Cancer Prevention European Journal of Cancer Prevention, Lippincott, Williams & Wilkins, 2016, 25 (2), pp.109-14. ⟨10.1097/CEJ.0000000000000153⟩ |
| ISSN: | 0959-8278 1473-5709 |
| DOI: | 10.1097/CEJ.0000000000000153〉 |
| Popis: | IF 2.415; International audience; The haemoglobin concentration measured by faecal immunochemical tests (FIT) may be decreased in cases of delayed sample return or high temperature. It is an issue of great importance. The aim of this study was to investigate the effects of sample return time and of season on the performance of an FIT (FOB-Gold) with a new buffer. The study included 20 371 participants involved in the French organized colorectal cancer (CRC) screening programme. The probability of a positive screening test, detection rates and positive predictive values for CRC and advanced adenoma were analysed according to sample return time and season of screening. A sample of positive FIT was stored for 7 days in an incubator at 20°C or 30°C. The positivity rate was 4.1% for a sample return time of up to 3 days, 4.1% for 4-5 days and 4.6% for 6-7 days (P=0.25). In multivariate analysis, there was no association between positivity rates, detection rates and positive predictive values for CRC and advanced adenoma and the sample return time or the season of screening. At a constant temperature of 20°C, there was a decrease in the haemoglobin concentration of 5.1% after 7 days. The decrease reached 20.5% at a temperature of 30°C. It was only 4.5% during the first 4 days of storage in the incubator. With the new buffer, delay in sample return or season did not affect the clinical outcome. When temperatures reach 30°C, the faecal sample must be returned promptly. |
| Databáze: | OpenAIRE |
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