Three-dimensional surface and ultrasound imaging for daily IGRT of prostate cancer

Autor: G. Apicella, Marco Krengli, C. Pisani, Debora Beldì, Valentina Amisano, Gianfranco Loi, Marco Brambilla
Rok vydání: 2016
Předmět:
Zdroj: Radiation Oncology (London, England)
ISSN: 1748-717X
DOI: 10.1186/s13014-016-0734-3
Popis: Background Image guided radiotherapy (IGRT) is an essential pre-requisite for delivering high precision radiotherapy. We compared daily variation detected by two non-ionizing imaging modalities (surface imaging and trans-abdominal ultrasound, US) to verify prostate patient setup and internal organ variations. Methods Forty patients with organ confined prostate cancer and candidates to curative radiotherapy were enrolled in this prospective study. At each treatment session, after laser alignment, all patients received imaging by a 3D-surface and a 3D-US system. The shifts along the three directions (anterior-posterior AP, cranial-caudal CC, and later-lateral LL) were measured in terms of systematic and random errors. Then, we performed statistical analysis on the differences and the possible correlations between the two modalities. Results For both IGRT modalities, surface imaging and US, 1318 acquisitions were collected. According with Shapiro Wilk test, the positioning error distributions were not Gaussian for both modalities. The differences between the systematic errors detected by the two modalities were statistically significant only in LL direction (p
Databáze: OpenAIRE