The Prevalence of and Risk Factors for Barrett's Esophagus in a Korean Population
| Autor: | Byung Sung Ko, Jong Jae Park, Byeong Gwan Kim, Ji Won Kim, Jae Woo Kim, Jae Young Jang, Seon Mee Park, Soo Heon Park, Hyun Jin Kim, Kang Seok Seo, Nayoung Kim, Moon Kyung Joo, Moon Gi Chung, Su Youn Nam, Youn Seon Choi, Jin Il Kim, Mee Yon Cho, Gwang Ho Baik, Hyun Chae Jung, In-Sik Chung, Byung Kyu Nah |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Chest Pain medicine.medical_specialty Adolescent Gastroenterology Hiatal hernia Barrett Esophagus Young Adult Sex Factors Risk Factors Internal medicine Prevalence Humans Mass Screening Medicine Endoscopy Digestive System Prospective Studies Reflux esophagitis Risk factor Esophagitis Peptic Aged Korea medicine.diagnostic_test business.industry Esophageal disease Esophagogastroduodenoscopy Anti-Inflammatory Agents Non-Steroidal Age Factors Odds ratio Middle Aged medicine.disease Hernia Hiatal Barrett's esophagus Multivariate Analysis Female business Esophagitis |
| Zdroj: | Journal of Clinical Gastroenterology. 43:907-914 |
| ISSN: | 0192-0790 |
| Popis: | OBJECTIVE The aim of this study was to evaluate the prevalence of Barrett's esophagus (BE) in the general Korean population by evaluating screening esophagogastroduodenoscopy. In addition, the risk factors for BE were identified. METHOD An esophagogastroduodenoscopy examination was performed in 25,536 subjects who had upper endoscopy screening from January 2006 to July 2006. RESULTS Two hundred and fifteen subjects were confirmed to have BE by pathology, thus the prevalence of BE was calculated to be 0.84%. The endoscopic findings were subdivided into 2 groups: BE without reflux esophagitis (RE), which included 167 (77.7%), and BE with RE, which included 48 (22.3%). The analysis of symptoms showed that only 60.1% of the subjects with BE had reflux symptoms. Chest pain [odds ratio (OR): 1.48, 95% confidence interval (CI): 1.04-2.11] and epigastric soreness (OR: 1.42, 95% CI: 1.05-1.93) were found more frequently in the subjects with BE compared with the normal subjects. The multivariate analysis showed that the risk factors for all subjects with BE were a male sex (OR: 1.82, 95% CI: 1.32-2.50), nonsteroidal anti-inflammatory drug use (OR: 2.02, 95% CI: 1.28-3.20), hiatal hernia (OR: 5.66, 95% CI: 3.70-8.66), and an age > or = 60 compared with an age < 40 (OR: 1.81, 95% CI: 1.07-3.09). There was no significant difference associated with RE. CONCLUSIONS The prevalence of BE in Korean patients presenting for a routine health check-up was 0.84%, lower than reported in Western countries. Among the subjects with BE 77.7% did not have endoscopic erosions and there were no reflux symptoms in 39.9%. These results suggest that regular endoscopic screening with a high index of suspicion is necessary for the diagnosis of BE. |
| Databáze: | OpenAIRE |
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