Virulence-associated characteristics and phage lysogenicity of two morphologically distinct colonies of Vibrio cholerae O139 serogroup
| Autor: | Galina A. Yeroshenko, N. I. Smirnova, L. F. Livanova, Galina V. Chekhovskaya, Natalia I. Davidova |
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| Rok vydání: | 1996 |
| Předmět: |
viruses
Colony Count Microbial Virulence medicine.disease_cause Microbiology Pilus Bacteriophage Lethal Dose 50 Mice Vibrionaceae Lysogenic cycle Genetics medicine Animals Molecular Biology Lysogeny Vibrio cholerae Bacterial Capsules biology Proteolytic enzymes Chromosomes Bacterial biology.organism_classification Temperateness |
| Zdroj: | FEMS microbiology letters. 136(2) |
| ISSN: | 0378-1097 |
| Popis: | The presence of a temperate phage was demonstrated in a strain of Vibrio cholerae O139 isolated from a patient. Spontaneous variants with translucent colonies had lost this phage. The loss of the phage was associated with increased hydrophobicity, indicating the loss of the capsule. These clones were sensitive to serum bactericidal activity, showed decreased expression of such presumed virulence factors as proteases, motility and mannose-sensitive pili. Furthermore, excision of the phage made the strain dependent on purines for growth. |
| Databáze: | OpenAIRE |
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