Synthesis of 2′,2′-difluoro-6,7-dihydro-16-methylenecyclopropa[6,7]progesterone analogues

Autor:	Pierre Crabbé, Humberto Carpio, John H Fried
Rok vydání:	1973
Předmět:	Cyclopropanes Structure-Activity Relationship Reaction sequence Stereochemistry Chemistry Hydrolysis Pregnadienes Methods Fluorine Progestins Progesterone
Zdroj:	J. Chem. Soc., Perkin Trans. 1. :227-230
ISSN:	1364-5463 0300-922X
DOI:	10.1039/p19730000227
Popis:	17α-Acetoxy-2′,2′,6β-trifluoro-6β,7β-dihydro-16-methylenecyclopropa[6,7]progesterone (9) and its Δ1-analogue (10) have been synthesised by a ten-step reaction sequence from 3-hydroxy-16-methylpregna-5,16-dien-20-one (1).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5740b439203eb58d6ef44f4f84c0abb https://doi.org/10.1039/p19730000227 Zobrazit plný text záznamu