How to approach genome wars in sepsis?
| Autor: | Jack J. Hawiger, James M. Musser |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Lung business.industry Genomics Critical Care and Intensive Care Medicine medicine.disease Genome Multiorgan failure United States Microcirculation Sepsis medicine.anatomical_structure Genomic technology medicine Commentary Humans Endothelial dysfunction Intensive care medicine business Microvascular endothelium National Heart Lung and Blood Institute (U.S.) |
| Zdroj: | Critical Care |
| ISSN: | 1466-609X 1364-8535 |
| Popis: | Sepsis continues to pose a clear challenge as one of the most difficult and costly problems to treat and prevent. Sepsis is caused by systemic or localized infections that damage the integrity of microcirculation in multiple organs. The challenge of sepsis and its long-term sequelae was addressed by the National Institutes of Health National Heart Lung and Blood Institute Division of Blood Diseases and Resources. Defining sepsis as severe endothelial dysfunction syndrome that causes multiorgan failure in response to intravascular or extravascular microbial agents, the National Heart Lung and Blood Institute panel proposed the concept of genome wars as a platform for new diagnostic, therapeutic, and preventive approaches to sepsis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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