Association Between Antidiarrheal Drug Prescription and Return Visits Among Adult Patients With Acute Diarrhea
| Autor: | Yasuhiro Osugi, Daiki Kobayashi, Kenichiro Ishiguro |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Drug
medicine.medical_specialty Acute diarrhea medicine.drug_class media_common.quotation_subject Antibiotics Infectious Disease return visit Internal medicine medicine Internal Medicine Medical prescription media_common Adult patients business.industry General Engineering Gastroenterology acute diarrhea antidiarrheal drug Retrospective cohort study Odds ratio japan Diarrhea admission medicine.symptom business |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Whether antidiarrheal medications have benefits or demerits when administered to adult patients with diarrhea remains controversial. We aimed to evaluate the association between antidiarrheal drug prescription and clinical outcomes in adult patients with acute diarrhea. This retrospective cohort study was conducted by collecting secondary data of patients' health records at St. Luke's International Hospital from April 1, 2004, to March 31, 2016. We included all participants aged 20-59 years who visited the division of general internal medicine or the emergency room in the hospital due to acute diarrheal symptoms. We excluded those who had chronic diarrhea or were immunocompromised (e.g., those with cancer or immunosuppressant usage). Our primary outcome was return visits within two weeks; the secondary outcome was admission to the hospital due to acute diarrhea within two weeks from the first visit. We compared the outcomes between patients with and without antidiarrheal drug prescriptions. During the study period, a total of 10,246 patients were included, of which 204 (2.0%) were prescribed antidiarrheal drugs. The mean age of the patients was 35.0 (standard deviation: 10.7) years, and 4,130 (40.3%) were men. Patients who were prescribed antidiarrheal drugs were more likely to be prescribed antibiotics (p |
| Databáze: | OpenAIRE |
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