Effects of delta sleep inducing peptide on sleep cycle of cats deprived of paradoxical sleep
| Autor: | Gordana Maširević, Veselinka Šušić |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Male
medicine.medical_specialty Physiology Sleep REM Electroencephalography Biochemistry 03 medical and health sciences 0302 clinical medicine Delta Sleep-Inducing Peptide Internal medicine medicine Animals Injections Intraventricular First episode 0303 health sciences CATS medicine.diagnostic_test biology business.industry 030302 biochemistry & molecular biology Fissipedia biology.organism_classification Sleep in non-human animals Sleep deprivation Endocrinology Anesthesia Cats Delta sleep-inducing peptide Sleep Deprivation Wakefulness medicine.symptom business Sleep Oligopeptides 030217 neurology & neurosurgery |
| Zdroj: | Archives internationales de physiologie et de biochimie. 93(4) |
| ISSN: | 0003-9799 |
| Popis: | The effect of synthetic delta sleep inducing peptide (DSIP) on sleep was investigated in cat. DSIP (7 nmol/kg was administered intracerebroventricularly to cats deprived of paradoxical sleep (PS) for 72 h and immediately after termination of PS deprivation an injection of either Ringer or DSIP solution was given. Eight h of recovery sleep was then recorded. DSIP failed to affect the duration of slow-wave sleep, PS and total sleep time. There was, however, significant decrease of wakefulness and light slow-wave sleep (S1) while deep slow-wave sleep (S2) was significantly increased. There was also no change in the latency to the first episode of S2 sleep and PS. Thus, we conclude that DSIP altered the relative amounts of S1 and S2 sleep, causing more S2 (delta) sleep at the time when pressure for sleep was at its highest due to prior sleep deprivation. |
| Databáze: | OpenAIRE |
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