Chemotherapeutic treatment of colorectal cancer in pregnancy: case report
| Autor: | Khadija Al-Khatani, Ziyad Makoshi, Claire Perrott, Fadia Al-Mohaisen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Oncology
Adult medicine.medical_specialty Organoplatinum Compounds Colorectal cancer medicine.medical_treatment Ovariectomy Saudi Arabia Leucovorin Case Report Adenocarcinoma FOLFOX Surgical oncology Pregnancy Internal medicine Antineoplastic Combined Chemotherapy Protocols Medicine Chemotherapy Humans Medicine(all) Ovarian Neoplasms business.industry Liver Neoplasms General Medicine medicine.disease Oxaliplatin Fluorouracil Female business Colorectal Neoplasms Pregnancy Complications Neoplastic medicine.drug |
| Zdroj: | Journal of Medical Case Reports |
| ISSN: | 1752-1947 |
| Popis: | Introduction Colon cancer in pregnancy is uncommon. Only a small number of case reports have been published in the literature on the use of chemotherapeutic drugs during pregnancy. Reports of such cases assist clinicians in further investigating the use of chemotherapy in pregnancy. Case presentation FOLFOX-6 was administered to a pregnant, 33-year-old Saudi woman with metastatic colon cancer from 22 to 30 weeks of gestation. Her cancer was diagnosed during her pregnancy. She tolerated the chemotherapy well and delivered a full-term baby girl with no obvious harm, and normal development was documented at her 2-year follow-up examination. Conclusion Colon cancer during pregnancy is not easily detected and is difficult to manage. A detailed history and high clinical suspicion are needed in patients who present with symptoms and signs suggestive of malignancy. A multidisciplinary approach with patient involvement is needed to decrease morbidity and mortality caused by both treatment and the cancer in the mother and to limit side effects for the fetus. Further data and long-term follow-up are needed to better understand the potential long-term side effects of chemotherapeutic drugs on offspring. |
| Databáze: | OpenAIRE |
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