The Prevalence of Hand-mirror Cells in Acute Myeloblastic and Lymphoblastic Leukemia
| Autor: | Jeannette Pullen, David R. Head, Benjamin Humphrey, Lizardo Cerezo |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Acute leukemia Cell type Adolescent business.industry T cell Cell General Medicine T lymphocyte medicine.disease Leukemia Lymphoid Leukemia Myeloid Acute Leukemia medicine.anatomical_structure Immune system Acute lymphocytic leukemia Immunology Neoplastic Stem Cells medicine Humans Child business Retrospective Studies |
| Zdroj: | American Journal of Clinical Pathology. 81:355-357 |
| ISSN: | 1943-7722 0002-9173 |
| DOI: | 10.1093/ajcp/81.3.355 |
| Popis: | To evaluate the prevalence and significance of hand-mirror cells (HMC) in acute leukemia, 214 cases were studied retrospectively. They were classified by FAB and included 102 pediatric and 112 adult cases. Greater than 10% HMC were found in 6.5%. No overall difference was noted with age group, though HMC were more common in lymphoblastic cases (10% versus 3%). However, the greatest number of HMC were found in four adult cases, three of which were myeloblastic. Of the lymphoblastic cases with greater than 10% HMC, T and B studies were done in three that were typed as one T cell and two non-T cell (L1, CALL+; L3, sIg+). Forty-eight other cases with less than 10% HMC included 13 T cell and 35 non-T cell. The authors conclude that HMC may not correlate with morphologic or immune cell type and they do not appear to be a specific marker for a type of lymphoblastic and/or T-cell leukemia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|