Lumbar Spine Paraspinal Muscle and Intervertebral Disc Height Changes in Astronauts After Long-Duration Spaceflight on the International Space Station

Autor: Alan R. Hargens, Robert M. Healey, Jeffrey C. Lotz, Alexander J. Snyder, Scott E. Parazynski, Jojo V. Sayson, Brandon R. Macias, Jeannie F. Bailey, Dezba Coughlin, Douglas G. Chang
Rok vydání: 2016
Předmět:
Male
0301 basic medicine
Time Factors
Supine position
law.invention
0302 clinical medicine
Deconditioning
law
aerospace medicine
Back pain
magnetic resonance imaging
Orthopedics and Sports Medicine
Prospective Studies
Intervertebral Disc
weightlessness
Lumbar Vertebrae
Weightlessness
Middle Aged
Magnetic Resonance Imaging
medicine.anatomical_structure
Astronauts
Biomedical Imaging
Female
muscles
medicine.symptom
medicine.medical_specialty
Clinical Sciences
Paraspinal Muscles
Biomedical Engineering
back pain
Lumbar vertebrae
Spaceflight
spine
Article
03 medical and health sciences
Lumbar
atrophy
medicine
Humans
business.industry
Lumbosacral Region
Intervertebral disc
Space Flight
Surgery
Orthopedics
030104 developmental biology
Musculoskeletal
immobilization
Neurology (clinical)
Nuclear medicine
business
030217 neurology & neurosurgery
Zdroj: Spine, vol 41, iss 24
ISSN: 1528-1159
0362-2436
DOI: 10.1097/brs.0000000000001873
Popis: STUDY DESIGN Prospective case series. OBJECTIVE Evaluate lumbar paraspinal muscle (PSM) cross-sectional area and intervertebral disc (IVD) height changes induced by a 6-month space mission on the International Space Station. The long-term objective of this project is to promote spine health and prevent spinal injury during space missions and here on Earth. SUMMARY OF BACKGROUND DATA National Aeronautics and Space Administration (NASA) crewmembers have a 4.3 times higher risk of herniated IVDs, compared with the general and military aviator populations. The highest risk occurs during the first year after a mission. Microgravity exposure during long-duration spaceflights results in approximately 5 cm lengthening of body height, spinal pain, and skeletal deconditioning. How the PSMs and IVDs respond during spaceflight is not well described. METHODS Six NASA crewmembers were imaged supine with a 3 Tesla magnetic resonance imaging. Imaging was conducted preflight, immediately postflight, and then 33 to 67 days after landing. Functional cross-sectional area (FCSA) measurements of the PSMs were performed at the L3-4 level. FCSA was measured by grayscale thresholding within the posterior lumbar extensors to isolate lean muscle on T2-weighted scans. IVD heights were measured at the anterior, middle, and posterior sections of all lumbar levels. Repeated measures analysis of variance was used to determine significance at P
Databáze: OpenAIRE
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